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20 publications

Journal ArticleAug 27, 2026Research

Integrated CT Foundation Model and Radiomic Features Define Clinically and Biologically Distinct Colorectal Cancer Subtypes

Du Cai^†, Haoning Qi^†, Qiuxia Yang^†, Yibin Zhao^†, Chenghang Li, Chuling Hu, Yinmeng Zhang, Rende Huang, Wenjun Mao^*, Xiaojian Wu^*, Yize Mao^*, Feng Gao^*

Source document DOI

Journal ArticleMar 19, 2026CGH

INTELCAPE: A Deep Learning-Powered System for Automated, High-Accuracy Crohn's Disease Diagnosis via Capsule Endoscopy

De-Jun Fan^†, Yize Mao^†, Feng Liang^†, Zheng Liu^†, Huayu Li^†, Jian Tang, Yanan Liu, Mingjie Wang, Yuting Qian, Jie Chen, Neng Wang, Tao Yang, Shuangyi Tan, Guanbin Li^*, Feng Gao^*, Jiancong Hu^*, Xiaojian Wu^*

Code Source document DOI

Journal ArticleMar 11, 2026Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

Chuling Hu^†, Du Cai^†, Weiqiang You^†, Zhengran Zhou^†, Junwei Liu, Cheng-Hang Li, Min-Yi Lv, Bao-Wen Gai, Chong Chen, Xinxin Huang, Run Xian Wang, Xiao-Jian Wu^*, Peishan Hu^*, Feng Gao^*

Source document DOI

Journal ArticleSep 14, 2025NAR

PCsRNAdb: a comprehensive resource of small noncoding RNAs across cancers

Ren-de Huang^†, Jiang Li^†, Qi Cao^†, Lixia Wang^†, Zhixiong Shao, Haochun Yang, Xinlei Zhang, Chuanlai Yang, Xiangya Kong, Qiuyue Gu, Jianmin Wu, Tsan-Yu Chiu, Penghu Lian^*, Kui Wu^*, Feng Gao^*, Zhongxu Zhu^*

Code Project DOI

Journal ArticleJul 23, 2025Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

Jing Yang^†, Du Cai^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-ao Wang, Cheng-hang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng Gao^*, Xiaojian Wu^*

DOI

Journal ArticleJul 18, 2025TMI

SegMamba-V2: Long-range Sequential Modeling Mamba For General 3D Medical Image Segmentation

Zhaohu Xing^†, Tian Ye, Yijun Yang, Du Cai, Baowen Gai, Xiao-Jian Wu^*, Feng Gao^*, Lei Zhu^*

Code DOI

Journal ArticleJul 16, 2025Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

Du Cai^†, Haoning Qi^†, Qiuxia Yang^†, Huayu Li^†, Cheng-hang Li, Chuling Hu, Baowen Gai, Xu Zhang, Yize Mao^*, Feng Gao^*, Xiaojian Wu^*

DOI

Journal ArticleMar 7, 2025Advanced Science

Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer

Feng Gao^†, Junxiang Ding^†, Baowen Gai^†, Du Cai^†, Chuling Hu, Feng-Ao Wang, Ruikun He, Junwei Liu^*, Yixue Li^*, Xiao-Jian Wu^*

DOI

Journal ArticleFeb 27, 2025Genomics Proteomics Bioinformatics

Challenges in AI-driven Biomedical Multimodal Data Fusion and Analysis

Junwei Liu^†, Xiaoping Cen^†, Chenxin Yi, Feng-Ao Wang, Junxiang Ding, Jinyu Cheng, Qinhua Wu, Baowen Gai, Yiwen Zhou, Ruikun He, Feng Gao^*, Yixue Li^*

PMID DOI

Journal ArticleSep 1, 2024International Journal of Surgery

Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study

Jia-Xin Lei^†, Runxian Wang^†, Chuling Hu, Xiaoying Lou, Min-Yi Lv, Cheng-hang Li, Baowen Gai, Xiao-Jian Wu^*, Ruoxu Dou^*, Du Cai^*, Feng Gao^*

PMID DOI

Journal ArticleJun 6, 2024Genome Biology

TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology

Feng-Ao Wang^†, Zhenfeng Zhuang^†, Feng Gao^†, Ruikun He, Shaoting Zhang, Liansheng Wang^*, Junwei Liu^*, Yixue Li^*

PMID DOI

Journal ArticleJun 26, 2023MedComm

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

Min-Yi Lv^†, Du Cai^†, Cheng-Hang Li^†, Junguo Chen^†, Guanman Li, Chuling Hu, Baowen Gai, Jiaxin Lei, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng Gao^*

PMID DOI

Journal ArticleAug 1, 2022Medical Image Analysis

Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images

Feng Gao^†*, Minhao Hu^†, Min-Er Zhong^†, Shixiang Feng, Xuwei Tian, Xiaochun Meng, Ze-ping Huang, Min-yi Lv, Tao Song, Xiaofan Zhang^*, Xiangguang Zou^*, Xiaojian Wu^*

PMID DOI

Journal ArticleMar 25, 2021Nature Communications

Predicting treatment response from longitudinal images using multi-task deep learning

Cheng Jin^†, Heng Yu^†, Jia Ke^†, Peirong Ding^†, Yongju Yi, Xiaofeng Jiang, Xin Duan, Jinghua Tang, Daniel T. Chang, Xiaojian Wu^*, Feng Gao^*, Ruijiang Li^*

PMID DOI

Journal ArticleAug 16, 2019Oncogenesis

DeepCC: a novel deep learning-based framework for cancer molecular subtype classification

Feng Gao^†, Wei Wang, Miaomiao Tan, Lina Zhu, Yuchen Zhang, Evelyn Fessler, Louis Vermeulen, Xin Wang^*

PMID DOI

Journal ArticleJun 1, 2019Gastroenterology

Gene expression signature in surgical tissues and endoscopic biopsies identifies high-risk T1 colorectal cancers

Raju Kandimalla^†, Tsuyoshi Ozawa^†, Feng Gao^†, Xin Wang^*, Ajay Goel^*, T1 Colorectal Cancer Study Group

DOI

Journal ArticleMay 1, 2019Annals of Surgery

Genome-wide discovery of a novel gene-expression signature for the identification of lymph node metastasis in esophageal squamous cell carcinoma

Fuminori Sonohara^†, Feng Gao^†, Naoki Iwata, Mitsuro Kanda, Masahiko Koike, Naoki Takahashi, Yasuhide Yamada, Yasuhiro Kodera, Xin Wang^*, Ajay Goel^*

DOI

Journal ArticleMar 1, 2019EBioMedicine

A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer

Daisuke Izumi^†, Feng Gao^†, Shusuke Toden, Fuminori Sonohara, Mitsuro Kanda, Takatsugu Ishimoto, Yasuhiro Kodera, Xin Wang, Hideo Baba^*, Ajay Goel^*

PMID DOI

Journal ArticleAug 15, 2018Clinical Cancer Research

Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer

Raju Kandimalla^†, Feng Gao^†, Takatoshi Matsuyama, Toshiaki Ishikawa, Hiroyuki Uetake, Naoki Takahashi, Yasuhide Yamada, Carlos Becerra, Scott Kopetz, Xin Wang, Ajay Goel

DOI

Journal ArticleMar 1, 2018Gastroenterology

A microRNA signature associated with metastasis of T1 colorectal cancers to lymph nodes

Tsuyoshi Ozawa^†, Raju Kandimalla^†, Feng Gao^†, Hiroaki Nozawa, Keisuke Hata, Hiroshi Nagata, Satoshi Okada, Daisuke Izumi, Hideo Baba, James Fleshman, Xin Wang, Toshiaki Watanabe, Ajay Goel^*

DOI