2026
Cancer Letters
Biography
Dr. Chuling Hu is a postdoctoral researcher at the Sixth Affiliated Hospital of Sun Yat-sen University. He completed his doctoral training in surgery in 2026 and continues to study colorectal cancer through bioinformatics, deep learning, and clinically useful AI model development.
Research Interests
- Colorectal Cancer
- Artificial Intelligence
Education
- Postdoctoral FellowThe Sixth Affiliated Hospital of Sun Yat-sen University2026 - now
- Doctor of Medicine in SurgerySun Yat-sen University2021 - 2026
- Bachelor of Medicine in Clinical MedicineSun Yat-sen University2016 - 2021
Lab highlights
Highlighted publications
2025
Advanced Science
CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning
2025
Nature Communications
Personalized risk stratification in colorectal cancer via PIANOS system
All related publications
† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members
Journal Article
2026
Cancer Letters
Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition
Chu-Ling HU†, Du CAI†, Weiqiang You†, Zhengran Zhou†, Junwei Liu, Cheng-Hang LI, Min-Yi LV, Bao-Wen GAI, Chong Chen, Xinxin Huang, Run-Xian WANG, Xiao-Jian Wu*, Peishan Hu*, Feng GAO*
Journal Article
2026
Cell Death & Disease
Lactylation of SLC26A3 in the acidic tumor microenvironment promotes malignant progression of colorectal carcinoma
Chong Chen†, Du CAI†, Xuanhui Liu†, Yifan Zheng, Xinxin Huang, Dongwen Chen, Jiawei Cai, Yiran Bie, Zhengran Zhou, Chu-Ling HU, Zhengyu Wei, Kuntai Cai, Ting Li, Shuzhen Luo, Dongbing Liu, Kui Wu, Zerong Cai, Feng GAO, Xiaojian Wu*, Peishan Hu*
Journal Article
2026
Diagnostics
Translating Molecular Subtypes into Cost-Effective Radiogenomic Biomarkers for Prognosis of Colorectal Cancer
Journal Article
2025
Advanced Science
CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning
Jing Yang†, Du CAI†, Junwei Liu†, Zhenfeng Zhuang†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang*, Feng GAO*, Xiaojian Wu*
Journal Article
2025
Nature Communications
Personalized risk stratification in colorectal cancer via PIANOS system
Du CAI†, Hao-Ning QI†, Qiuxia Yang†, Huayu Li†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao*, Feng GAO*, Xiaojian Wu*
Journal Article
2025
Advanced Science
Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer
Feng GAO†, Junxiang Ding†, Bao-Wen GAI†, Du CAI†, Chu-Ling HU, Feng-Ao Wang, Ruikun He, Junwei Liu*, Yixue Li*, Xiao-Jian Wu*
Journal Article
2024
International Journal of Surgery
Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study
Jia-Xin LEI†, Run-Xian WANG†, Chu-Ling HU, Xiaoying Lou, Min-Yi LV, Cheng-Hang LI, Bao-Wen GAI, Xiao-Jian Wu*, Ruoxu Dou*, Du CAI*, Feng GAO*
Journal Article
2023
MedComm
Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies
Min-Yi LV†, Du CAI†, Cheng-Hang LI†, Junguo Chen†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan*, Xiaojian Wu*, Xiaosheng He*, Feng GAO*
Conference Paper
2023
Gastroenterology
Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies
Min-Yi LV†, Du CAI, Cheng-Hang LI, Junguo Chen, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan, Feng GAO, Xiaosheng He*
Journal Article
2023
Cancer Medicine
An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer
Du CAI†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiao-Jian Wu*, Feng GAO*
Journal Article
2022
Frontiers in Genetics
Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature
Chu-Ling HU†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiao-Jian Wu, Feng GAO*
Conference Paper
2022
Journal of Clinical Oncology
A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.
Chu-Ling HU†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiaojian Wu, Feng GAO*
Journal Article
2022
Frontiers in Genetics
Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer
Cheng-Hang LI†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO*
Journal Article
2022
Frontiers in Genetics
DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients
Min-Yi LV†, Wei Wang†, Min-Er ZHONG†, Du CAI, De-Jun FAN, Cheng-Hang LI, Wei-Bin KOU, Ze-Ping HUANG, Xin DUAN, Chu-Ling HU, Qi-Qi ZHU, Xiao-Sheng He, Feng GAO*
Conference Paper
2021
Journal of Clinical Oncology
Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.
Qi-Qi ZHU†, Du CAI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO*
Conference Paper
2021
Journal of Clinical Oncology
Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.
Du CAI†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO*
Conference Paper
2021
Journal of Clinical Oncology
A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer
Min-Er ZHONG†, Du CAI, De-Jun FAN, Wei Wang, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xiaojian Wu, Feng GAO*