Cheng-Hang LI

Research Assistant

Cancer Institute, Peking University & HKUST Medical Center

Biography

Cheng-Hang LI completed an MEng in Computer Science and Technology with joint supervision from the Sixth Affiliated Hospital and the School of Computer Science and Engineering at Sun Yat-sen University. He later completed an MPhil in Artificial Intelligence at The Hong Kong University of Science and Technology (Guangzhou). At the Cancer Institute of Peking University and HKUST Medical Center, his work applies deep learning to multi-omics, computational pathology, radiology, and survival analysis in cancer research.

Research Interests

Deep Learning
Feature Fusion

Education

MPhil in Artificial IntelligenceThe Hong Kong University of Science and Technology Guangzhou2022 - 2024
MEng in Computer Science and TechnologySun Yat-sen University2019 - 2022
BEng in Polymer Materials and ScienceSichuan University2015 - 2019

Lab highlights

Highlighted publications

2026Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

2025Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

2025Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

All related publications

Journal ArticleMar 11, 2026Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

Chuling Hu^†, Du Cai^†, Weiqiang You^†, Zhengran Zhou^†, Junwei Liu, Cheng-Hang Li, Min-Yi Lv, Bao-Wen Gai, Chong Chen, Xinxin Huang, Run Xian Wang, Xiao-Jian Wu^*, Peishan Hu^*, Feng Gao^*

Source document DOI

Journal ArticleJan 14, 2026Diagnostics

Translating Molecular Subtypes into Cost-Effective Radiogenomic Biomarkers for Prognosis of Colorectal Cancer

Baowen Gai^†, Xin Duan, Chenghang Li, Chuling Hu, Minyi Lv, Jiaxin Lei, Runxian Wang, Feng Gao^*, Du Cai^*

Journal ArticleDec 4, 2025Cancer Science

Decoding Senescence-Driven Heterogeneity in Early-Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Du Cai^†, Mingru Mai^†, Rende Huang^†, Haoning Qi, Xingzhi Feng, Qianling Gao, Yinmeng Zhang, Chenghang Li, Xiaojian Wu^*, Yize Mao^*, Zihuan Yang^*, Feng Gao^*

Journal ArticleJul 23, 2025Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

Jing Yang^†, Du Cai^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-ao Wang, Cheng-hang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng Gao^*, Xiaojian Wu^*

Journal ArticleJul 16, 2025Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

Du Cai^†, Haoning Qi^†, Qiuxia Yang^†, Huayu Li^†, Cheng-hang Li, Chuling Hu, Baowen Gai, Xu Zhang, Yize Mao^*, Feng Gao^*, Xiaojian Wu^*

Journal ArticleSep 1, 2024International Journal of Surgery

Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study

Jia-Xin Lei^†, Runxian Wang^†, Chuling Hu, Xiaoying Lou, Min-Yi Lv, Cheng-hang Li, Baowen Gai, Xiao-Jian Wu^*, Ruoxu Dou^*, Du Cai^*, Feng Gao^*

Journal ArticleApr 12, 2024IEEE Transactions on Medical Imaging

Structure Embedded Nucleus Classification for Histopathology Images

Wei Lou^†, Xiang Wan, Guanbin Li, Xiaoying Lou, Cheng-Hang Li, Feng Gao, Haofeng Li^*

Journal ArticleJun 26, 2023MedComm

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

Min-Yi Lv^†, Du Cai^†, Cheng-Hang Li^†, Junguo Chen^†, Guanman Li, Chuling Hu, Baowen Gai, Jiaxin Lei, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng Gao^*

Conference PaperMay 1, 2023Gastroenterology

Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies

Min-Yi Lv, Du Cai, Cheng-Hang Li, Junguo Chen, Guanman Li, Chuling Hu, Baowen Gai, Jia-xin Lei, Ping Lan, Feng Gao, Xiaosheng He

Journal ArticleApr 1, 2023Cancer Medicine

An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer

Du Cai^†, Wei Wang, Min-Er Zhong, Dejun Fan, Xuanhui Liu, Cheng-Hang Li, Ze-Ping Huang, Qiqi Zhu, Min-Yi Lv, Chuling Hu, Xin Duan, Xiao-Jian Wu^*, Feng Gao^*

Journal ArticleDec 8, 2022Journal of Translational Medicine

CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study

Min-Er Zhong^†, Xin Duan^†, Ma-yi-di-li Ni-jia-ti, Haoning Qi, Dongwei Xu, Du Cai, Cheng-Hang Li, Zeping Huang, Qiqi Zhu, Feng Gao^*, Xiaojian Wu^*

Journal ArticleSep 7, 2022Frontiers in Genetics

Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature

Chuling Hu^†, Du Cai, Min-Er Zhong, Dejun Fan, Cheng-Hang Li, Min-Yi Lv, Ze-Ping Huang, Wei Wang, Xiao-Jian Wu, Feng Gao^*

Journal ArticleJun 30, 2022Frontiers in Oncology

A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer

Min-Er Zhong^†, Ze-Ping Huang^†, Xun Wang^†, Du Cai, Cheng-Hang Li, Feng Gao^*, Xiao-Jian Wu^*, Wei Wang^*

Conference PaperJun 1, 2022Journal of Clinical Oncology

A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.

Chuling Hu, Du Cai, Min-Er Zhong, De-jun Fan, Cheng-Hang Li, Min-Yi Lv, Ze-Ping Huang, Wei Wang, Xiaojian Wu, Feng Gao

Journal ArticleMay 12, 2022Frontiers in Genetics

Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer

Cheng-Hang Li^†, Du Cai, Min-Er Zhong, Min-Yi Lv, Ze-Ping Huang, Qiqi Zhu, Chuling Hu, Haoning Qi, Xiaojian Wu, Feng Gao^*

Conference PaperMay 1, 2022Gastroenterology

PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer

Du Cai, Haoning Qi, Wei Wang, Min-Er Zhong, De-jun Fan, Cheng-Hang Li, Xiaojian Wu, Feng Gao

Journal ArticleMar 11, 2022Frontiers in Genetics

DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients

Min-yi Lv^†, Wei Wang^†, Min-Er Zhong^†, Du Cai, De-jun Fan, Cheng-hang Li, Wei-Bin Kou, Ze-ping Huang, Xin Duan, Chuling Hu, Qiqi Zhu, Xiao-sheng He, Feng Gao^*

Conference PaperMay 20, 2021Journal of Clinical Oncology

Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.

Du Cai, Wei Wang, Min-Er Zhong, De-jun Fan, Xuanhui Liu, Cheng-Hang Li, Ze-Ping Huang, Qiqi Zhu, Min-Yi Lv, Chuling Hu, Xin Duan, Xiaojian Wu, Feng Gao

Conference PaperMay 20, 2021Journal of Clinical Oncology

A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer

Min-Er Zhong, Du Cai, De-jun Fan, Wei Wang, Cheng-Hang Li, Ze-Ping Huang, Qiqi Zhu, Min-Yi Lv, Chuling Hu, Xiaojian Wu, Feng Gao

Conference PaperMay 20, 2021Journal of Clinical Oncology

Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.

Qiqi Zhu, Du Cai, Wei Wang, Min-Er Zhong, De-jun Fan, Xuanhui Liu, Cheng-Hang Li, Ze-Ping Huang, Min-Yi Lv, Chuling Hu, Xin Duan, Xiaojian Wu, Feng Gao

Showing the 20 most recent of 23 related publications.