Bao-Wen GAI

PhD Student

Biography

Bao-Wen GAI is a PhD student in Surgery at Sun Yat-sen University. His research focuses on colorectal cancer and artificial intelligence for diagnosis and prognosis.

Research Interests

Colorectal Cancer
Artificial Intelligence

Education

Doctor of Medicine in SurgerySun Yat-sen University2022 - Present
Bachelor of Medicine in Clinical MedicineSun Yat-sen University2017 - 2022

Lab highlights

Highlighted publications

2026Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

2025Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

2025TMI

SegMamba-V2: Long-range Sequential Modeling Mamba For General 3D Medical Image Segmentation

All related publications

PreprintJul 9, 2026medRxiv

In Vivo Spatial Transcriptomics for Bleeding-free Profiling Human Internal Organs

DOI

Conference PaperMay 1, 2026Gastroenterology

UNRAVELING THE IMPACT OF INSOMNIA ON COLORECTAL CANCER: MICROBIOME DYSBIOSIS, IMMUNOSUPPRESSIVE MICROENVIRONMENT, AND THERAPEUTIC IMPLICATIONS

Yinmeng Zhang, Du Cai, Jiahui Zhao, He Zhu, Yan Xia, Baowen Gai, Haoning Qi, Chuling Hu, Rende Huang, Mingru Mai, Nan Zhang, Xiao-Jian Wu, Hong Xu, Feng Gao

DOI

Journal ArticleMar 25, 2026Frontiers in Endocrinology

Real-world performance of open-source large language models in diabetes diagnosis

Shuting Yang^†, Sujie Liu^†, Yuxi Ma^†, Baowen Gai, Junwei Liu, Liansheng Wang^*, Feng Gao^*, Zhiguang Zhou^*

Source document DOI

Journal ArticleMar 11, 2026Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

Chuling Hu^†, Du Cai^†, Weiqiang You^†, Zhengran Zhou^†, Junwei Liu, Cheng-Hang Li, Min-Yi Lv, Bao-Wen Gai, Chong Chen, Xinxin Huang, Run Xian Wang, Xiao-Jian Wu^*, Peishan Hu^*, Feng Gao^*

Source document DOI

Journal ArticleJan 14, 2026Diagnostics

Translating Molecular Subtypes into Cost-Effective Radiogenomic Biomarkers for Prognosis of Colorectal Cancer

Baowen Gai^†, Xin Duan, Chenghang Li, Chuling Hu, Minyi Lv, Jiaxin Lei, Runxian Wang, Feng Gao^*, Du Cai^*

DOI

Journal ArticleJul 23, 2025Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

Jing Yang^†, Du Cai^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-ao Wang, Cheng-hang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng Gao^*, Xiaojian Wu^*

DOI

Journal ArticleJul 18, 2025TMI

SegMamba-V2: Long-range Sequential Modeling Mamba For General 3D Medical Image Segmentation

Zhaohu Xing^†, Tian Ye, Yijun Yang, Du Cai, Baowen Gai, Xiao-Jian Wu^*, Feng Gao^*, Lei Zhu^*

Code DOI

Journal ArticleJul 16, 2025Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

Du Cai^†, Haoning Qi^†, Qiuxia Yang^†, Huayu Li^†, Cheng-hang Li, Chuling Hu, Baowen Gai, Xu Zhang, Yize Mao^*, Feng Gao^*, Xiaojian Wu^*

DOI

Journal ArticleMar 7, 2025Advanced Science

Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer

Feng Gao^†, Junxiang Ding^†, Baowen Gai^†, Du Cai^†, Chuling Hu, Feng-Ao Wang, Ruikun He, Junwei Liu^*, Yixue Li^*, Xiao-Jian Wu^*

DOI

Journal ArticleFeb 27, 2025Genomics Proteomics Bioinformatics

Challenges in AI-driven Biomedical Multimodal Data Fusion and Analysis

Junwei Liu^†, Xiaoping Cen^†, Chenxin Yi, Feng-Ao Wang, Junxiang Ding, Jinyu Cheng, Qinhua Wu, Baowen Gai, Yiwen Zhou, Ruikun He, Feng Gao^*, Yixue Li^*

PMID DOI

Journal ArticleNov 19, 2024Nature Communications

Single-cell encoded gene silencing for high-throughput combinatorial siRNA screening

Feng Guo^†, Xianglin Ji^†, Chuxiao Xiong, Hailiang Sun, Zhenghua Liang, Richard Yan-Do, Baowen Gai, Feng Gao, Linfeng Huang, Zhongping Li, Becki Yi Kuang, Peng Shi^*

DOI

Journal ArticleSep 1, 2024International Journal of Surgery

Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study

Jia-Xin Lei^†, Runxian Wang^†, Chuling Hu, Xiaoying Lou, Min-Yi Lv, Cheng-hang Li, Baowen Gai, Xiao-Jian Wu^*, Ruoxu Dou^*, Du Cai^*, Feng Gao^*

PMID DOI

Journal ArticleJun 26, 2023MedComm

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

Min-Yi Lv^†, Du Cai^†, Cheng-Hang Li^†, Junguo Chen^†, Guanman Li, Chuling Hu, Baowen Gai, Jiaxin Lei, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng Gao^*

PMID DOI

Conference PaperMay 1, 2023Gastroenterology

Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies

Min-Yi Lv, Du Cai, Cheng-Hang Li, Junguo Chen, Guanman Li, Chuling Hu, Baowen Gai, Jia-xin Lei, Ping Lan, Feng Gao, Xiaosheng He

DOI