Building the AI-Native Future Hospital
Reconstructing Healthcare with AI-Native Technologies.
We bridge Micro-scale (Omics), Meso-scale (Imaging), and Macro-scale (Clinical) data to transform medical services into intelligent, precision-driven care.

Research Areas

Omics AI & Mechanisms

Explainability First. We design modular networks (e.g., TMO-Net) that map predictions directly to gene pathways, decoding the “Black Box” for trusted mechanism discovery.

Multimodal Foundation Models

All-in-One Perception. Leveraging Self-Supervised Learning to unify genomic, pathological, and radiological data (CRCFound), overcoming annotation bottlenecks.

Surgery & Embodied AI

Perception to Action. Advancing from AR navigation to robot cognitive control, empowering surgeons with “transparent vision” and autonomous assistance.

Clinical Reasoning & Agents

Infinite Context. We decouple reasoning from knowledge, using Agents to orchestrate guidelines and evidence for transparent, traceable clinical decisions.

Team

Principal Investigator

Feng GAO

Feng GAO

Professor

My research leverages AI and big data to improve diagnostics, prognostics, and ultimately, outcomes in cancer and other biomedical fields.

Artificial Intelligence Colorectal Cancer

Senior Faculty

Xiao-Tong Luo

Xiao-Tong Luo

Associate Professor

My research integrates bioinformatics, algorithm development, and data analytics to advance early cancer diagnosis, prognostic stratification, and immunotherapy.

Bioinformatics Artificial Intelligence
De-Jun FAN

De-Jun FAN

Associate Professor

My research explores the intersection of gastrointestinal endoscopy (GIE) and artificial intelligence (AI), along with the biological mechanisms of colorectal cancer development.

Gastrointestinal Endoscopy Artificial Intelligence
Chao WANG

Chao WANG

Associate Professor

I have been engaged in the subspecialties of gastrointestinal pathology and breast pathology for more than ten years and am also a senior member of the MDT team.

Gastrointestinal Pathology Digital Pathology

Staff

Jie-Yu CHEN

Jie-Yu CHEN

Dentist

I am a dentist interested in orthodontics and AI-assisted imaging analysis.

Deep Learning Orthodontics
Shu-Ting YANG

Shu-Ting YANG

Physician

An endocrinologist passionate about artificial intelligence and diabetes, focusing on applying machine learning and bioinformatics to diabetes heterogeneity research.

Artificial Intelligence Endocrinology
Qi-Qi ZHU

Qi-Qi ZHU

Surgeon

I am a surgeon focusing on colorectal cancer and translational bioinformatics in clinical practice.

Bioinformatics Colorectal Cancer
Feng ZHANG

Feng ZHANG

Physician

I am a PhD student studying intestinal microecology and host immunity in translational biomedical research.

Intestinal Microecology Human Immunity
Du CAI

Du CAI

Postdoc

I focus on leveraging explainable AI and large foundation models to advance medical imaging and digital pathology in colorectal cancer research.

Artificial Intelligence Colorectal Cancer
Hao-Ning QI

Hao-Ning QI

Postdoc

I am a postdoctoral researcher working on AI for colorectal cancer with a focus on clinically actionable models.

Colorectal Cancer Artificial Intelligence
Jin-Ping CHEN

Jin-Ping CHEN

Postdoc

My research involves the analysis of brain structure and functional imaging in pituitary adenomas, as well as emotion and cognition.

Neuroimaging analysis Pituitary adenoma
Jia-Xin LEI

Jia-Xin LEI

Research Assitant

I am a research assistant interested in deep learning and medical image analysis for clinical applications.

Deep Learning
Cheng-Hang LI

Cheng-Hang LI

Research Assistant

I am a research assistant focusing on deep learning, multimodal feature fusion, and medical AI system development.

Deep Learning Feature Fusion

Current Students

Min-Yi LV

Min-Yi LV

PhD Student

I am a PhD student focusing on colorectal cancer research, biostatistics, and evidence-driven clinical modeling.

Colorectal Cancer Biostatistics
Chu-Ling HU

Chu-Ling HU

PhD Student

I am a PhD student focusing on AI-driven colorectal cancer research and clinically useful model development.

Colorectal Cancer Artificial Intelligence
Bao-Wen GAI

Bao-Wen GAI

PhD Student

I am a PhD student working on AI methods for colorectal cancer diagnosis and prognosis.

Colorectal Cancer Artificial Intelligence
Ke-Cheng WU

Ke-Cheng WU

PhD Student

I am a PhD student working on deep learning and medical image analysis for intelligent surgical applications.

Deep Learning Medical Image Analysis
Yin-Meng ZHANG

Yin-Meng ZHANG

PhD Student

I am a PhD student working on AI methods for colorectal cancer research and translational clinical applications.

Colorectal Cancer Artificial Intelligence
Chong-Xiang GAO

Chong-Xiang GAO

PhD Student

I am a PhD student studying AI applications in urology, with interests in clinically oriented translational research.

Urology Artificial Intelligence
Jun XIANG

Jun XIANG

PhD Student

My research leverages AI and big data to improve diagnostics, prognostics, and ultimately, outcomes in colorectal cancer.

Artificial Intelligence Colorectal Cancer
Ren-De HUANG

Ren-De HUANG

Research Student

I am a research student working on AI methods for colorectal cancer analysis and clinical decision support.

Colorectal Cancer Artificial Intelligence
Yi-Yi ZUO

Yi-Yi ZUO

Research Student

I focus on bioinformatics and non-coding RNA research, particularly in calcific aortic valve disease and translational medicine.

Non-coding RNA Bioinformatics
Shu-Xin ZHENG

Shu-Xin ZHENG

Research Student

My research focuses on neoantigen discovery, tumor bioinformatics, and the development of bioinformatics databases.

Bioinformatics Neoantigen
Shun-Hui DENG

Shun-Hui DENG

Research Student

My research focuses on neoantigen discovery, tumor bioinformatics, and the development of bioinformatics databases.

Bioinformatics Neoantigen
Hui-Ting TANG

Hui-Ting TANG

Research Student

I work at the intersection of AI and genodermatoses, focusing on multimodal large language models for skin cancer screening and diagnosis in rare inherited skin diseases.

Artificial Intelligence Genodermatoses
Wen DONG

Wen DONG

Research Student

Wen DONG is a master's student in Dermatology. She is pursuing her degree at the Sixth Affiliated Hospital of Sun Yat-sen University. She is now interested in studying genetic skin diseases.

Genodermatosis Artificial Intelligence
Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

(2025). Journal Article PCsRNAdb: a comprehensive resource of small noncoding RNAs across cancers. NAR.
(2025). Journal Article CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning. Advanced Science.
(2025). Journal Article Personalized risk stratification in colorectal cancer via PIANOS system. Nature Communications.
(2025). Journal Article Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer. Advanced Science.
(2025). Journal Article Challenges in AI-driven Biomedical Multimodal Data Fusion and Analysis. Genomics Proteomics Bioinformatics.
News

Contact

Visit Our Lab

The Sixth Affiliated Hospital of Sun Yat-sen University

No.26, Road yuancun-er-heng, Tianhe

Guangzhou, Guangdong 510006

China

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