Xiaojian Wu

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Journal Article 2026 CGH

INTELCAPE: A Deep Learning-Powered System for Automated, High-Accuracy Crohn's Disease Diagnosis via Capsule Endoscopy

De-Jun FAN^†, Yize Mao^†, Feng Liang^†, Zheng Liu^†, Huayu Li^†, Jian Tang, Yanan Liu, Mingjie Wang, Yuting Qian, Jie Chen, Neng Wang, Tao Yang, Shuangyi Tan, Guanbin Li^*, Feng GAO^*, Jiancong Hu^*, Xiaojian Wu^*

Code Source Document DOI

Journal Article 2026 Cell Death & Disease

Lactylation of SLC26A3 in the acidic tumor microenvironment promotes malignant progression of colorectal carcinoma

Chong Chen^†, Du CAI^†, Xuanhui Liu^†, Yifan Zheng, Xinxin Huang, Dongwen Chen, Jiawei Cai, Yiran Bie, Zhengran Zhou, Chu-Ling HU, Zhengyu Wei, Kuntai Cai, Ting Li, Shuzhen Luo, Dongbing Liu, Kui Wu, Zerong Cai, Feng GAO, Xiaojian Wu^*, Peishan Hu^*

Journal Article 2025 Cancer Science

Decoding Senescence-Driven Heterogeneity in Early-Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Du CAI^†, Ming-Ru MAI^†, Ren-De HUANG^†, Hao-Ning QI, Xingzhi Feng, Qianling Gao, Yin-Meng ZHANG, Cheng-Hang LI, Xiaojian Wu^*, Yize Mao^*, Zihuan Yang^*, Feng GAO^*

Journal Article 2025 Cell Genomics

Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC

Haitao Xiang^†, Xiangyu Guan^†, Yaohua Wei^†, Shuzhen Luo^†, Haibo Zhang^†, Fanyu Bu, Yixin Yan, Yunyun Fu, Yijian Li, Qumiao Xu, Penghui Lin, Dongbing Liu, Xinlan Zhou, Feng GAO, Tai Chen, Guangjun Nie, Kui Wu, Ying Gu, Longqi Liu, Ziqing Ye^*, Xiaojian Wu^*, Ruifang Zhao^*, Siqi Liu^*, Xuan Dong^*

Journal Article 2025 iScience

A plasma metabolite-based test to detect minimal residual disease in post-surgery patients with colorectal cancer

Zhengran Zhou^†, Richard Mortensen^†, Peishan Hu^†, Bo Jin, Xiao-Bin Zheng, Xiao Li, James Schilling, C. James Chou, Karl G. Sylvester, Yanghai Cong, Xiaojian Wu, Feng GAO^*, Xuefeng B. Ling^*, Xuanhui Liu^*

Journal Article 2025 Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

Jing Yang^†, Du CAI^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng GAO^*, Xiaojian Wu^*

Journal Article 2025 Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

Du CAI^†, Hao-Ning QI^†, Qiuxia Yang^†, Huayu Li^†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao^*, Feng GAO^*, Xiaojian Wu^*

Journal Article 2023 Diseases of the Colon & Rectum

A Longitudinal MRI-Based Artificial Intelligence System to Predict Pathological Complete Response After Neoadjuvant Therapy in Rectal Cancer: A Multicenter Validation Study

Jia Ke^†, Cheng Jin^†, Jinghua Tang^†, Haimei Cao^†, Songbing He^†, Peirong Ding, Xiaofeng Jiang, Hengyu Zhao, Wuteng Cao, Xiaochun Meng, Feng GAO, Ping Lan, Ruijiang Li^*, Xiaojian Wu^*

PMID DOI

Journal Article 2023 MedComm

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

Min-Yi LV^†, Du CAI^†, Cheng-Hang LI^†, Junguo Chen^†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng GAO^*

PMID DOI

Conference Paper 2023 International Digestive Disease Forum

Immunological profiling of human colorectal cancer defines four distinct molecular subtypes

Weiqiang You^†, Du CAI, Min-Yi LV, Peishan Hu, Feng GAO, Xiaojian Wu^*

Journal Article 2022 Journal of Translational Medicine

CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study

Min-Er ZHONG^†, Xin DUAN^†, Ma-Yi-Di-Li Ni-Jia-Ti, Hao-Ning QI, Dong-Wei XU, Du CAI, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Feng GAO^*, Xiaojian Wu^*

PMID DOI

Journal Article 2022 Medical Image Analysis

Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images

Feng GAO^†^*, Minhao Hu^†, Min-Er ZHONG^†, Shixiang Feng, Xuwei Tian, Xiaochun Meng, Ze-Ping HUANG, Min-Yi LV, Tao Song, Xiaofan Zhang^*, Xiangguang Zou^*, Xiaojian Wu^*

PMID DOI

Conference Paper 2022 Journal of Clinical Oncology

A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiaojian Wu, Feng GAO^*

Journal Article 2022 Frontiers in Genetics

Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer

Cheng-Hang LI^†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO^*

Conference Paper 2022 Gastroenterology

PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer

Du CAI^†, Hao-Ning QI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Xiaojian Wu, Feng GAO^*

Journal Article 2022 European Radiology

The growth pattern of liver metastases on MRI predicts early recurrence in patients with colorectal cancer: a multicenter study

Qian Cai^†, Yi-Ze Mao^†, Si-Qi Dai^†, Feng GAO^†, Qian Xiao, Wan-Ming Hu, Tao Qin, Qiu-Xia Yang, Zhao-Zhou Li, Du CAI, Min-Er ZHONG, Ke-Feng Ding^*, Xiaojian Wu^*, Rong Zhang^*

PMID DOI

Conference Paper 2021 Journal of Clinical Oncology

Multi-omics longitudinal analyses in stages I to III CRC patients: Surveillance liquid biopsy test to predict early recurrence and enable risk-stratified postoperative CRC management.

Xuanhui Liu^†, Yani Zhang, Xiurui Zhu, Sheeno P. Thyparambil, Wei-Li Liao, Xiao-Bin Zheng, Jin You, Ashiq Masood, Zhen Li, Gabriel Yang, Xiaoming Yao, Shiying Hao, Robert Heaton, James Schilling, Karl G. Sylvester, Jiayu Liao, Feng GAO, Ping Lan, Xuefeng Ling, Xiaojian Wu^*

Conference Paper 2021 Journal of Clinical Oncology

Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.

Qi-Qi ZHU^†, Du CAI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^*

Conference Paper 2021 Journal of Clinical Oncology

Genome-wide analysis indicating cancer associated fibroblast (CAF) impacts on colorectal cancer (CRC) prognosis via immunosuppression.

Yu-Feng Chen^†, Xiaojian Wu, Feng GAO^*

Conference Paper 2021 Journal of Clinical Oncology

Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^*

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