Xin Wang

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Journal Article 2025 ESMO Gastrointest Oncol

Poor-prognosis young-onset colorectal cancer is defined by the mesenchymal subtype and can be predicted by integrating molecular and histopathological characteristics

Jia Ke^†, Ying Li^†, Lin Qi^†, Xiang Li, Wei Wang, Sanne Ten Hoorn, Yin Zhu, Hao Huang, Feng GAO, Louis Vermeulen, Xin Wang^*

Journal Article 2025 Gut

Liquid biopsy to identify Barrett's oesophagus, dysplasia and oesophageal adenocarcinoma: the EMERALD multicentre study

Jinsei Miyoshi^†, Alessandro Mannucci^†, Marco Scarpa, Feng GAO, Shusuke Toden, Timothy Whitsett, Landon J Inge, Ross M Bremner, Tetsuji Takayama, Yulan Cheng, Teodoro Bottiglieri, Iris D Nagetaal, Martha J Shrubsole, Ali H Zaidi, Xin Wang, Helen G Coleman, Lesley a Anderson, Stephen J Meltzer, Ajay Goel^*

PMID Trial Registration Dataset DOI

Journal Article 2023 Neuron

Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair

Ngan Pan Bennett Au^†, Tan Wu, Xinyu Chen, Feng GAO, Yuen Tung Yolanda Li, Wing Yip Tam, Kwan Ngok Yu, Daniel H Geschwind, Giovanni Coppola, Xin Wang, Chi Him Eddie Ma^*

PMID DOI

Journal Article 2023 iScience

Deep learning-derived spatial organization features on histology images predicts prognosis in colorectal liver metastasis patients after hepatectomy

Lin Qi^†, Jie-Ying Liang^†, Zhong-Wu Li, Shao-Yan Xi, Yu-Ni Lai, Feng GAO, Xian-Rui Zhang, De-Shen Wang, Ming-Tao Hu, Yi Cao, Li-Jian Xu, Ronald C K Chan, Bao-Cai Xing, Xin Wang^*, Yu-Hong Li^*

Conference Paper 2023 Journal of Clinical Oncology

Deep learning-derived spatial organization features on histopathology images to predict prognosis in patients with colorectal liver metastasis, after hepatectomy.

Xin Wang^†, Yu-Hong Li, Baocai Xing, Lin Qi, Jie-Ying Liang, Zhong-Wu Li, Shao-Yan Xi, Yu-Ni Lai, Feng GAO, De-Shen Wang, Ming-Tao Hu, Yi Cao, Xian-Rui Zhang, Li-Jian Xu, Ronald CK Chan^*

Journal Article 2022 Molecular Cancer

A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

Jinsei Miyoshi^†, Zhongxu Zhu^†, Aiping Luo^†, Shusuke Toden^†, Xuantong Zhou, Daisuke Izumi, Mitsuro Kanda, Tetsuji Takayama, Iqbal M. Parker, Minjie Wang, Feng GAO, Ali H. Zaidi, Hideo Baba, Yasuhiro Kodera, Yongping Cui, Xin Wang^*, Zhihua Liu^*, Ajay Goel^*

PMID DOI

Journal Article 2022 Oncogene

Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence

Tongtong Kan^†, Shupeng Zhang, Shengtao Zhou, Ya Zhang, Yun Zhao, Yinghua Gao, Tao Zhang, Feng GAO, Xin Wang, Linjie Zhao, Mengsu Yang^*

Journal Article 2021 Clinical Cancer Research

OCaMIR—a noninvasive, diagnostic signature for early-stage ovarian cancer: a multi-cohort retrospective and prospective study

Raju Kandimalla^†, Wei Wang, Fan Yu, Nianxin Zhou, Feng GAO, Monique Spillman, Lucie Moukova, Ondrej Slaby, Bodour Salhia, Shengtao Zhou^*, Xin Wang^*, Ajay Goel^*

Journal Article 2021 Medicine in Omics

Identification of prognostic spatial organization features in colorectal cancer microenvironment using deep learning on histopathology images

Lin Qi^†, Jia Ke, Zhaoliang Yu, Yi Cao, Yuni Lai, Yufeng Chen, Feng GAO^*, Xin Wang^*

Book Chapter 2020 Detection Methods in Precision Medicine

Genome-wide Discovery of MicroRNA Biomarkers for Cancer Precision Medicine

Zhongxu Zhu^†, Guiyuan Han, Hao Huang, Lingli He, Yu Chen, Jia Ke, Feng GAO, Louis Vermeulen, Xin Wang^*

Conference Paper 2019 Annals of Oncology

Identification, development and validation of a circulating miRNA-based diagnostic signature for early detection of gastric cancer

Daisuke Izumi^†, Feng GAO, Yuetong Chen, Takatsugu Ishimoto, Kei Horino, Shu Shimada, Yasuhiro Kodera, Hideo Baba, Jinfei Chen, Xin Wang, Ajay Goel^*

Journal Article 2019 Hepatology

Long-Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor-Specific Isoforms

Hui Chen^†, Feng GAO^†, Mian He^†, Xiao Fan Ding, Aikha M. Wong, Siu Ching Sze, Allen C. Yu, Tingting Sun, Anthony W.-H. Chan, Xin Wang^*, Nathalie Wong^*

PMID DOI

Journal Article 2019 Oncogenesis

DeepCC: a novel deep learning-based framework for cancer molecular subtype classification

Feng GAO^†, Wei Wang, Miaomiao Tan, Lina Zhu, Yuchen Zhang, Evelyn Fessler, Louis Vermeulen, Xin Wang^*

PMID DOI

Journal Article 2019 Gastroenterology

Gene expression signature in surgical tissues and endoscopic biopsies identifies high-risk T1 colorectal cancers

Raju Kandimalla^†, Tsuyoshi Ozawa^†, Feng GAO^†, Xin Wang^*, Ajay Goel^*, T1 Colorectal Cancer Study Group

Journal Article 2019 npj Precision Oncology

RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level

Raju Kandimalla^†, Feng GAO^†, Ying Li^†, Hao Huang, Jia Ke, Xin Deng, Linjie Zhao, Shengtao Zhou, Ajay Goel^*, Xin Wang^*

PMID DOI

Journal Article 2019 Annals of Surgery

Genome-wide discovery of a novel gene-expression signature for the identification of lymph node metastasis in esophageal squamous cell carcinoma

Fuminori Sonohara^†, Feng GAO^†, Naoki Iwata, Mitsuro Kanda, Masahiko Koike, Naoki Takahashi, Yasuhide Yamada, Yasuhiro Kodera, Xin Wang^*, Ajay Goel^*

Journal Article 2019 Seminars in Cancer Biology

Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities

Wei Wang^†, Raju Kandimalla^†, Hao Huang^†, Lina Zhu, Ying Li, Feng GAO, Ajay Goel, Xin Wang^*

Journal Article 2019 EBioMedicine

A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer

Daisuke Izumi^†, Feng GAO^†, Shusuke Toden, Fuminori Sonohara, Mitsuro Kanda, Takatsugu Ishimoto, Yasuhiro Kodera, Xin Wang, Hideo Baba^*, Ajay Goel^*

PMID DOI

Journal Article 2018 Leukemia and Lymphoma

Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML

Rodica P. Bunaciu^†, Robert J. MacDonald, Holly A. Jensen, Feng GAO, Xin Wang, Lynn Johnson, Jeffrey D. Varner, Andrew Yen^*

PMID DOI

Journal Article 2018 Nature Communications

High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients

Zhen Xu^†, Peilin Fang, Bingzhe Xu, Yufeng Lu, Jinghui Xiong, Feng GAO, Xin Wang, Jun Fan, Peng Shi^*

PMID DOI

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