Tumor Microenvironment

Lactylation of SLC26A3 in the acidic tumor microenvironment promotes malignant progression of colorectal carcinoma

This work investigates how the acidic tumor microenvironment drives colorectal cancer progression through protein lactylation. The authors show that lactylation decreases SLC26A3 …

Chong Chen

• Jan 21, 2026 • 1 min read

Journal Article

The role of tertiary lymphoid structures in renal cell carcinoma: From predictive biomarker to therapeutic target

In the evolving landscape of cancer immunotherapy, tertiary lymphoid structures (TLS) have rapidly transitioned from a histological curiosity to a central mediator of anti-tumour …

Chong-Xiang GAO

• Sep 3, 2025 • 1 min read