Microsatellite Instability

Certain pMMR colorectal cancer patients should undergo additional MSI-PCR testing to reduce the risk of misdiagnosing MSI-H and Lynch syndrome

This study analyzed colorectal cancers with proficient mismatch repair by immunohistochemistry but high microsatellite instability by PCR to characterize when discordance matters …

Jing-Lin HUANG

• Jul 1, 2025 • 1 min read

Journal Article

Head-to-head comparative study: evaluating three panels for MSI-PCR testing in patients with colorectal and gastric cancer

This study compared the NCI MSI-PCR panel with two mononucleotide marker panels in a large Chinese cohort of colorectal and gastric cancers. The mononucleotide panels reduced MSI-L …

Xinhui Fu

• Sep 19, 2024 • 1 min read

Journal Article

Prognosis and immunotherapy efficacy in dMMR&MSS colorectal cancer patients and an MSI status predicting model

This study examined colorectal cancers with deficient mismatch repair by immunohistochemistry but microsatellite-stable status by PCR and compared their outcomes with canonical …

Xinhui Fu

• Apr 5, 2024 • 1 min read