Protein-protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer
**Background:** Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with stem cell property. Increased evidence suggest that CSCs could be responsible for …
Zhao-Liang Yu
A metabolism-related radiomics signature for predicting the prognosis of colorectal cancer
**Background:** Radiomics refers to the extraction of a large amount of image information from medical images, which can provide decision support for clinicians. In this study, we …
Validation of the Swedish diabetes re-grouping scheme in adult-onset diabetes in China
**Context:** This study applied the Swedish novel data-driven classification in Chinese newly diagnosed diabetic patients and validated its adoptability. **Objective:** This study …
Xia Li
Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients
**Aim:** Immune-related genes are associated with the prognosis of colorectal cancer (CRC) patients. The aim of this study was to evaluate the impact of an immune-related gene …
Jia Ke
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers
Hippo-YAP signaling pathway functions in early lineage differentiation of pluripotent stem cells, but the detailed mechanisms remain elusive. We found that knockout (KO) of Mst1 …
Xiang Sun
Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor
All-trans retinoic acid (ATRA)-based differentiation therapy has been unsuccessful in treating t(15;17) negative acute myeloid leukemia (AML) patients, motivating interest in …
Asif Rashid