Journal Article

Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images

Since segmentation labeling is usually time-consuming and annotating medical images requires professional expertise, it is laborious to obtain a large-scale, high-quality annotated …

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Feng GAO

A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer

**Background:** Colorectal cancer (CRC) is a heterogeneous disease, and current classification systems are insufficient for stratifying patients with different risks. This study …

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Min-Er ZHONG

Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer

**Background:** Preoperative and postoperative evaluation of colorectal cancer (CRC) patients is crucial for subsequent treatment guidance. Our study aims to provide a timely and …

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Cheng-Hang LI

The growth pattern of liver metastases on MRI predicts early recurrence in patients with colorectal cancer: a multicenter study

**Objectives:** The multicenter study aimed to explore the relationship between the growth pattern of liver metastases on preoperative MRI and early recurrence in patients with …

Qian Cai

DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients

**Background:** Increasing evidence have depicted that DNA repair-related genes (DRGs) are associated with the prognosis of colorectal cancer (CRC) patients. Thus, the aim of this …

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Min-Yi LV

A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

**Background:** Currently, there is no clinically relevant non-invasive biomarker for early detection of esophageal squamous cell carcinoma (ESCC). Herein, we established and …

Jinsei Miyoshi

Dissecting Cellular Heterogeneity Based on Network Denoising of scRNA-seq Using Local Scaling Self-Diffusion

Identifying the phenotypes and interactions of various cells is the primary objective in cellular heterogeneity dissection. A key step of this methodology is to perform …

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Xin DUAN

Identification of an autophagy-related gene signature for the prediction of prognosis in early-stage colorectal cancer

**Purpose:** A certain number of early-stage colorectal cancer (CRC) patients suffer tumor recurrence after initial curative resection. In this context, an effective prognostic …

Xu-Tao Lin

Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

**Background:** Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there …

Yu-Feng Chen