In hepatic flexure and transverse colon cancer surgeries, mobilizing the right mesocolon and precisely dissecting the gastrocolic trunk of Henle (GTH) are crucial. Previous …
**Background:** Luminal B breast cancer is routinely treated with chemotherapy and endocrine therapy. However, its sensitivity to treatment remains heterogeneous; therefore, …
The use of combinatorial siRNAs shows great promise for drug discovery, but the identification of safe and effective siRNA combinations remains challenging. Here, we develop a …
This study compared the NCI MSI-PCR panel with two mononucleotide marker panels in a large Chinese cohort of colorectal and gastric cancers. The mononucleotide panels reduced MSI-L …
**Background**: Tertiary lymphoid structures (TLSs) exert a crucial role in the tumor microenvironment (TME), impacting tumor development, immune escape, and drug resistance. …
The classification of diabetes is undergoing a significant transformation. As advancements in medical technology and a deeper understanding of its etiology, traditional …
Molecular subtyping of cancer is a critical step towards more individualized therapy and provides important biological insights into cancer heterogeneity. Although gene expression …
Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties …
This study examined colorectal cancers with deficient mismatch repair by immunohistochemistry but microsatellite-stable status by PCR and compared their outcomes with canonical …
The molecular mechanisms underlying tumor development are highly intricate. For gastrointestinal tumors, comprehending and controlling the heterogeneous molecular mechanisms may …