Publications

Journal article

Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study

International Journal of Surgery (2024)
Journal article

A new vision of diabetes classification: A shift from clinical manifestation to etiological molecular mechanism

Journal of Practical Medicine / Shiyong Yixue Zazhi (2024)
Journal article

TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology

Genome Biology (2024)
Conference

Cross-Level Contrastive Learning and Consistency Constraint for Semi-Supervised Medical Image Segmentation

IEEE International Symposium on Biomedical Imaging (2024)
Journal article

Structure Embedded Nucleus Classification for Histopathology Images

IEEE Transactions on Medical Imaging (2024)
Journal article

Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair

Neuron (2023)
Journal article

A prognostic model for ovarian neoplasms established by an integrated analysis of 1580 transcriptomic profiles

Scientific Reports (2023)
Journal article

Deep learning-derived spatial organization features on histology images predicts prognosis in colorectal liver metastasis patients after hepatectomy

iScience (2023)
Journal article

Application of the Chinese Expert Consensus on Diabetes Classification in Clinical Practice

Zhonghua Nei Ke Za Zhi (Chinese Journal of Internal Medicine) (2023)
Journal article

The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 types of cancer: a system review and novel biomarker investigating

Cancer Immunology, Immunotherapy (2023)
Journal article

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

MedComm (2023)
Conference

Immunological profiling of human colorectal cancer defines four distinct molecular subtypes

International Digestive Disease Forum (2023)
Conference

Deep learning-derived spatial organization features on histopathology images to predict prognosis in patients with colorectal liver metastasis, after hepatectomy.

Journal of Clinical Oncology (2023)
Conference

Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies

Gastroenterology (2023)
Journal article

MiR-423-5p is a novel endogenous control for the quantification of circulating miRNAs in human esophageal squamous cell carcinoma

Heliyon (2023)
Journal article

An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer

Cancer Medicine (2023)
Journal article

Association between genetically predicted leukocyte telomere length and non-scarring alopecia: a two-sample Mendelian randomization study

Frontiers in Immunology (2023)
Conference

Multi-scope Analysis Driven Hierarchical Graph Transformer for Whole Slide Image Based Cancer Survival Prediction

Lecture Notes in Computer Science (2023)
Journal article

Medical knowledge-assisted machine learning technologies in individualized medicine

Frontiers in Molecular Biosciences (2023)
Journal article

CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study

Journal of Translational Medicine (2022)
Journal article

Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature

Frontiers in Genetics (2022)
Journal article

Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images

Medical Image Analysis (2022)
Journal article

A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer

Frontiers in Oncology (2022)
Conference

A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.

Journal of Clinical Oncology (2022)
Journal article

Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer

Frontiers in Genetics (2022)
Conference

PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer

Gastroenterology (2022)
Journal article

The growth pattern of liver metastases on MRI predicts early recurrence in patients with colorectal cancer: a multicenter study

European Radiology (2022)
Conference

Cross-level contrastive learning and consistency constraint for semi-supervised medical image segmentation

IEEE International Symposium on Biomedical Imaging (2022)
Journal article

DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients

Frontiers in Genetics (2022)
Journal article

A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

Molecular Cancer (2022)
Journal article

Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence

Oncogene (2022)
Journal article

Dissecting Cellular Heterogeneity Based on Network Denoising of scRNA-seq Using Local Scaling Self-Diffusion

Frontiers in Genetics (2022)
Conference

Lesion-aware dynamic kernel for polyp segmentation

Lecture Notes in Computer Science (2022)
Journal article

Identification of an autophagy-related gene signature for the prediction of prognosis in early-stage colorectal cancer

Frontiers in Genetics (2021)
Journal article

Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

Molecular Medicine (2021)
Journal article

OCaMIR—a noninvasive, diagnostic signature for early-stage ovarian cancer: a multi-cohort retrospective and prospective study

Clinical cancer research (2021)
Journal article

An interpretable computer-aided diagnosis method for periodontitis from panoramic radiographs

Frontiers in Physiology (2021)
Journal article

Genome-Wide analysis reveals hypoxic microenvironment is associated with immunosuppression in poor survival of stage II/III colorectal cancer patients

Frontiers in Medicine (2021)
Conference

Multi-omics longitudinal analyses in stages I to III CRC patients: Surveillance liquid biopsy test to predict early recurrence and enable risk-stratified postoperative CRC management.

Journal of Clinical Oncology (2021)
Conference

Integrated immune-related gene signature to predict clinical outcome for patients with luminal B breast cancer.

Journal of Clinical Oncology (2021)
Conference

Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.

Journal of Clinical Oncology (2021)
Conference

Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.

Journal of Clinical Oncology (2021)
Conference

A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer

Journal of Clinical Oncology (2021)
Conference

Su029 INTEGRATING PROGNOSIS-RELATED GENES WITH IMMUNE-RELATED GENE SIGNATURE FOR SURVIVAL STRATIFICATION OF EARLY-STAGE COLORECTAL CANCER

Gastroenterology (2021)
Conference

Deep transformers for fast small intestine grounding in capsule endoscope video

IEEE International Symposium on Biomedical Imaging (2021)
Journal article

Predicting treatment response from longitudinal images using multi-task deep learning

Nature Communications (2021)
Journal article

A novel cell-free DNA methylation-based model improves the early detection of colorectal cancer

Molecular Oncology (2021)
Journal article

Identification of prognostic spatial organization features in colorectal cancer microenvironment using deep learning on histopathology images

Medicine in Omics (2021)
Journal article

Response to Letter to the Editor from Knobler et al:“Validation of the Swedish Diabetes Regrouping Scheme in Adult-Onset Diabetes in China”

The Journal of Clinical Endocrinology & Metabolism (2021)
Journal article

Protein-protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer

Cancer Cell International (2021)
Journal article

A metabolism-related radiomics signature for predicting the prognosis of colorectal cancer

Frontiers in molecular biosciences (2021)

Genome-wide Discovery of MicroRNA Biomarkers for Cancer Precision Medicine

Detection Methods in Precision Medicine (2020)
Conference

Identification of a stemness-related gene signature for predicting prognosis of patients with adjuvant chemotherapy in colorectal cancer

Annals of Oncology (2020)
Journal article

Validation of the Swedish diabetes re-grouping scheme in adult-onset diabetes in China

The Journal of Clinical Endocrinology & Metabolism (2020)
Journal article

Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients

European Journal of Surgical Oncology (2020)
Journal article

Multiomics-based colorectal cancer molecular subtyping using local scaling network fusion

Journal of Computational Biology (2020)
Journal article

Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers

Nucleic Acids Research (2020)
Conference

Integrating diffusion components of multi-omics datasets with application to cancer molecular subtyping

Intelligent Systems for Molecular Biology (2020)
Conference

Development of a novel liquid biopsy test to diagnose and locate gastrointestinal cancers

Journal of Clinical Oncology (2020)
Conference

Automatic and Interpretable Model for Periodontitis Diagnosis in Panoramic Radiographs

Medical Image Computing and Computer Assisted Intervention (2020)
Journal article

Analysis of potential hub genes involved in the pathogenesis of Chinese type 1 diabetic patients

Annals of Translational Medicine (2020)
Journal article

Development and validation of an individualized gene expression-based signature to predict overall survival in metastatic colorectal cancer

Annals of Translational Medicine (2020)
Journal article

The potential application of Cordyceps in metabolic-related disorders

Phytotherapy Research (2020)
Journal article

Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma

Cancer Cell International (2020)
Journal article

Obesity-related glomerulopathy: a latent change in obesity requiring more attention

Kidney and Blood Pressure Research (2020)
Conference

Automatic and interpretable model for periodontitis diagnosis in panoramic radiographs

Lecture Notes in Computer Science (2020)
Journal article

Multiomics-Based Colorectal Cancer Molecular Subtyping Using Local Scaling Network Fusion

Journal of Computational Biology (2019)
Conference

Identification, development and validation of a circulating miRNA-based diagnostic signature for early detection of gastric cancer

Annals of Oncology (2019)
Journal article

A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients

Cancer Cell International (2019)
Journal article

Long-Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor-Specific Isoforms

Hepatology (2019)
Journal article

An immune-related gene pairs signature predicts overall survival in serous ovarian carcinoma

OncoTargets and Therapy (2019)
Journal article

DeepCC: a novel deep learning-based framework for cancer molecular subtype classification

Oncogenesis (2019)
Journal article

An immune-related gene signature predicts prognosis of gastric cancer

Medicine (2019)
Journal article

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Nature Communications (2019)
Journal article

A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction

BioRxiv (2019)
Journal article

Gene expression signature in surgical tissues and endoscopic biopsies identifies high-risk T1 colorectal cancers

Gastroenterology (2019)
Conference

Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients

Journal of Clinical Oncology (2019)
Conference

Pathway analysis of hypoxia-related factors in early colorectal cancer patients with poor prognosis.

Journal of Clinical Oncology (2019)
Journal article

RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level

npj Precision Oncology (2019)
Journal article

Genome-wide discovery of a novel gene-expression signature for the identification of lymph node metastasis in esophageal squamous cell carcinoma

Annals of surgery (2019)
Journal article

Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities

Seminars in Cancer Biology (2019)
Journal article

A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer

EBioMedicine (2019)
Journal article

Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML

Leukemia and Lymphoma (2018)
Journal article

High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients

Nature Communications (2018)
Journal article

Dissecting cancer heterogeneity based on dimension reduction of transcriptomic profiles using extreme learning machines

PLoS ONE (2018)
Journal article

Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer

Clinical Cancer Research (2018)
Conference

A Novel Non-Invasive Circulating Mirna Signature for Detection of Esophageal Adenocarcinoma

Gastroenterology (2018)
Conference

Dysregulation of m6A RNA methylation regulators in colorectal cancer: Clinical implication as prognostic biomarkers and potential therapeutic targets

Cancer Research (2018)
Journal article

A microRNA signature associated with metastasis of T1 colorectal cancers to lymph nodes

Gastroenterology (2018)
Journal article

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

Oncotarget (2018)

HTSanalyzeR2: An Ultra-Fast R/Bioconductor Package for High-Throughput Screens with Interactive Report

Intelligent Systems for Molecular Biology (2017)
Conference

Poor-prognosis nasopharyngeal carcinoma as defined by a molecularly distinct subgroup and prediction by a miRNA expression signature

Journal of Clinical Oncology (2017)
Conference

Identification, Development and Validation of a Circulating Mirna-Based Diagnostic Signature for Early Detection of Gastric Cancer

Gastroenterology (2017)
Conference

Genome-wide discovery and identification of a novel microrna signature for recurrence prediction in colorectal cancer

Cancer Research (2017)
Conference

A Novel Mirna-Based, Non-Invasive, Diagnostic Panel for Detection of Esophageal Squamous Cell Carcinoma

Gastroenterology (2017)
Conference

Genome-Wide Analysis Revealed a Robust Gene Expression Signature to Identify Lymph Node Metastasis in Submucosal Colorectal Cancer

Gastroenterology (2017)
Conference

A Novel Mirna Signature for the Detection of Lymph Node Metastasis in Submucosal Colorectal Cancer Patients

Gastroenterology (2017)

Part 1 Biomarkers for Precision Medicine

Clinical Chemistry and Laboratory Medicine (CCLM) (2017)