Publications

Journal article

Deciphering tertiary lymphoid structure heterogeneity reveals prognostic signature and therapeutic potentials for colorectal cancer: a multicenter retrospective cohort study

International Journal of Surgery (2024)
Journal article

TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology

Genome Biology (2024)

Cross-Level Contrastive Learning and Consistency Constraint for Semi-Supervised Medical Image Segmentation

IEEE International Symposium on Biomedical Imaging (2024)
Journal article

Structure Embedded Nucleus Classification for Histopathology Images

IEEE Transactions on Medical Imaging (2024)
Journal article

Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair

Neuron (2023)
Journal article

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

MedComm (2023)
Journal article

Segmentation Only Uses Sparse Annotations: Unified Weakly and Semi-Supervised Learning in Medical Images

Medical Image Analysis (2022)
Journal article

A Transcription Factor Signature Can Identify the CMS4 Subtype and Stratify the Prognostic Risk of Colorectal Cancer

Frontiers in Oncology (2022)
Journal article

Multi-Size Deep Learning Based Preoperative Computed Tomography Signature for Prognosis Prediction of Colorectal Cancer

Frontiers in Genetics (2022)
Journal article

The growth pattern of liver metastases on MRI predicts early recurrence in patients with colorectal cancer: a multicenter study

European Radiology (2022)
Journal article

DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients

Frontiers in Genetics (2022)
Journal article

A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

Molecular Cancer (2022)
Journal article

Dissecting Cellular Heterogeneity Based on Network Denoising of scRNA-seq Using Local Scaling Self-Diffusion

Frontiers in Genetics (2022)
Journal article

The enhanced cell cycle related to the response to adjuvant therapy in pancreatic ductal adenocarcinoma

Genomics (2022)
Journal article

Identification of an Autophagy-Related Gene Signature for the Prediction of Prognosis in Early-Stage Colorectal Cancer

Frontiers in Genetics (2021)
Journal article

Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

Molecular Medicine (2021)
Journal article

Genome-Wide Analysis Reveals Hypoxic Microenvironment Is Associated With Immunosuppression in Poor Survival of Stage II/III Colorectal Cancer Patients

Frontiers in Medicine (2021)
Journal article

Predicting treatment response from longitudinal images using multi-task deep learning

Nature Communications (2021)
Journal article

A novel cell-free DNA methylation-based model improves the early detection of colorectal cancer

Molecular Oncology (2021)
Journal article

Identification of prognostic spatial organization features in colorectal cancer microenvironment using deep learning on histopathology images

Medicine in Omics (2021)
Journal article

A Metabolism-Related Radiomics Signature for Predicting the Prognosis of Colorectal Cancer

Frontiers in Molecular Biosciences (2021)
Journal article

Protein-protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer

Cancer Cell International (2021)
Conference

Identification of a stemness-related gene signature for predicting prognosis of patients with adjuvant chemotherapy in colorectal cancer

Annals of Oncology (2020)
Journal article

Validation of the Swedish diabetes re-grouping scheme in adult-onset diabetes in China

The Journal of Clinical Endocrinology & Metabolism (2020)
Journal article

Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients

European Journal of Surgical Oncology (2020)
Journal article

Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers

Nucleic Acids Research (2020)
Conference

Integrating diffusion components of multi-omics datasets with application to cancer molecular subtyping

Intelligent Systems for Molecular Biology (2020)
Conference

Development of a novel liquid biopsy test to diagnose and locate gastrointestinal cancers

Journal of Clinical Oncology (2020)
Conference

Automatic and Interpretable Model for Periodontitis Diagnosis in Panoramic Radiographs

Medical Image Computing and Computer Assisted Intervention (2020)
Journal article

Development and validation of an individualized gene expression-based signature to predict overall survival in metastatic colorectal cancer

Annals of Translational Medicine (2020)
Journal article

Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma

Cancer cell International (2020)
Journal article

Multiomics-Based Colorectal Cancer Molecular Subtyping Using Local Scaling Network Fusion

Journal of Computational Biology (2019)
Journal article

A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients

Cancer Cell International (2019)
Journal article

Long-Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor-Specific Isoforms

Hepatology (2019)
Journal article

An immune-related gene pairs signature predicts overall survival in serous ovarian carcinoma

OncoTargets and Therapy (2019)
Journal article

DeepCC: a novel deep learning-based framework for cancer molecular subtype classification

Oncogenesis (2019)
Journal article

An immune-related gene signature predicts prognosis of gastric cancer

Medicine (2019)
Journal article

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Nature Communications (2019)
Journal article

Gene Expression Signature in Surgical Tissues and Endoscopic Biopsies Identifies High-Risk T1 Colorectal Cancers

Gastroenterology (2019)
Conference

Pathway analysis of hypoxia-related factors in early colorectal cancer patients with poor prognosis

Journal of Clinical Oncology (2019)
Conference

Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients

Journal of Clinical Oncology (2019)
Journal article

RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level

npj Precision Oncology (2019)
Journal article

Genome-wide Discovery of a Novel Gene-expression Signature for the Identification of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma

Annals of Surgery (2019)
Journal article

A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer

EBioMedicine (2019)
Journal article

Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML

Leukemia and Lymphoma (2018)
Journal article

High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients

Nature Communications (2018)
Journal article

Dissecting cancer heterogeneity based on dimension reduction of transcriptomic profiles using extreme learning machines

PLoS ONE (2018)
Journal article

Genome-wide Discovery and Identification of a Novel miRNA Signature for Recurrence Prediction in Stage II and III Colorectal Cancer

Clinical Cancer Research (2018)
Conference

A Novel Non-Invasive Circulating Mirna Signature for Detection of Esophageal Adenocarcinoma

Gastroenterology (2018)
Conference

Dysregulation of m6A RNA methylation regulators in colorectal cancer: Clinical implication as prognostic biomarkers and potential therapeutic targets

Cancer Research (2018)
Journal article

A MicroRNA Signature Associated With Metastasis of T1 Colorectal Cancers to Lymph Nodes

Gastroenterology (2018)
Conference

Poor-prognosis nasopharyngeal carcinoma as defined by a molecularly distinct subgroup and prediction by a miRNA expression signature

Journal of Clinical Oncology (2017)
Conference

Identification, Development and Validation of a Circulating Mirna-Based Diagnostic Signature for Early Detection of Gastric Cancer

Gastroenterology (2017)
Conference

Genome-wide discovery and identification of a novel microrna signature for recurrence prediction in colorectal cancer

Cancer Research (2017)
Conference

Genome-Wide Analysis Revealed a Robust Gene Expression Signature to Identify Lymph Node Metastasis in Submucosal Colorectal Cancer

Gastroenterology (2017)
Conference

A Novel Mirna-Based, Non-Invasive, Diagnostic Panel for Detection of Esophageal Squamous Cell Carcinoma

Gastroenterology (2017)
Conference

A Novel Mirna Signature for the Detection of Lymph Node Metastasis in Submucosal Colorectal Cancer Patients

Gastroenterology (2017)