Feng GAO

Professor

Biography

Dr. Feng Gao is a Professor of Medical AI at the Sixth Affiliated Hospital of Sun Yat-sen University and the data analysis lead for the ICGC-ARGO Colorectal Cancer project. Leveraging his interdisciplinary expertise in computer science and oncology, Dr. Gao’s lab is dedicated to building the critical technical infrastructure for the “AI-Native Future Hospital.” By pioneering “AI Doctor 3.0” through multi-agent systems, multimodal foundation models, and intelligent surgical computing, his team is driving the paradigm shift from passive medical tools to autonomous, collaborative clinical intelligence. Using colorectal cancer as a flagship testing ground, Dr. Gao focuses on architecture-driven AI paradigms—rather than mere parameter scaling—to create full-stack, scalable solutions that fundamentally restructure healthcare supply and delivery.

Research Interests

Artificial Intelligence
Colorectal Cancer

Education

Joint PhD in Cancer Biology and Bioinformatics
City University of Hong Kong & Cornell University
2015 - 2018
Visiting Student in Computer Science and Electronic Engineering
Kumamoto University
2007 - 2008
BEng in Computer Science and Technology
Shandong University
2005 - 2009

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Rodica P. Bunaciu^†, Robert J. MacDonald, Holly A. Jensen, Feng GAO, Xin Wang, Lynn Johnson, Jeffrey D. Varner, Andrew Yen^* (2018). Journal Article Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML. Leukemia and Lymphoma.

PMID DOI

Zhen Xu^†, Peilin Fang, Bingzhe Xu, Yufeng Lu, Jinghui Xiong, Feng GAO, Xin Wang, Jun Fan, Peng Shi^* (2018). Journal Article High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients. Nature Communications.

PMID DOI

Kejun Wang^†, Xin DUAN^†, Feng GAO^†, Wei Wang, Liangliang Liu, Xin Wang^* (2018). Journal Article Dissecting cancer heterogeneity based on dimension reduction of transcriptomic profiles using extreme learning machines. PLoS ONE.

PMID DOI

Raju Kandimalla^†, Feng GAO^†, Takatoshi Matsuyama, Toshiaki Ishikawa, Hiroyuki Uetake, Naoki Takahashi, Yasuhide Yamada, Carlos Becerra, Scott Kopetz, Xin Wang, Ajay Goel^* (2018). Journal Article Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer. Clinical Cancer Research.

Jinsei Miyoshi^†, Feng GAO, Shusuke Toden, Martha J. Shrubsole, Marco Scarpa, Timothy Whitsett, Landon Inge, Stephen J. Meltzer, Bottiglieri Teodoro, Helen G. Coleman, Lesley A. Anderson, Xin Wang, Ajay Goel^* (2018). Conference Paper A Novel Non-Invasive Circulating Mirna Signature for Detection of Esophageal Adenocarcinoma. Gastroenterology.

Raju Kandimalla^†, Feng GAO, Chun Ruan, Michael Hsieh, Xin Wang, Ajay Goel^* (2018). Conference Paper Dysregulation of m6A RNA methylation regulators in colorectal cancer: Clinical implication as prognostic biomarkers and potential therapeutic targets. Cancer Research.

Tsuyoshi Ozawa^†, Raju Kandimalla^†, Feng GAO^†, Hiroaki Nozawa, Keisuke Hata, Hiroshi Nagata, Satoshi Okada, Daisuke Izumi, Hideo Baba, James Fleshman, Xin Wang, Toshiaki Watanabe, Ajay Goel^* (2018). Journal Article A microRNA signature associated with metastasis of T1 colorectal cancers to lymph nodes. Gastroenterology.

Rodica P Bunaciu^†, Robert J MacDonald, Feng GAO, Lynn M Johnson, Jeffrey D Varner, Xin Wang, Sarah Nataraj, Monica L Guzman, Andrew Yen^* (2018). Journal Article Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment. Oncotarget.

Feng GAO^†, Xiupei Mei, Lina Zhu, Yuchen Zhang, Wei Wang, Xin Wang^* (2017). Conference Paper HTSanalyzeR2: An Ultra-Fast R/Bioconductor Package for High-Throughput Screens with Interactive Report. Intelligent Systems for Molecular Biology.

Lan Zhao^†, Feng GAO, Wei Wang, Xin DUAN, Yuchen Zhang, Lina Zhu, Xin Wang^* (2017). Conference Paper Poor-prognosis nasopharyngeal carcinoma as defined by a molecularly distinct subgroup and prediction by a miRNA expression signature. Journal of Clinical Oncology.

Daisuke Izumi^†, Shusuke Toden, Feng GAO, Jacob Turner, Mitsuro Kanda, Takatsugu Ishimoto, Yasuhiro Kodera, Xin Wang, Hideo Baba, Ajay Goel^* (2017). Conference Paper Identification, Development and Validation of a Circulating Mirna-Based Diagnostic Signature for Early Detection of Gastric Cancer. Gastroenterology.

Raju Kandimalla^†, Feng GAO, Naoki Takahashi, Yasuhide Yamada, Takatoshi Matsuyama, Toshiyaki Ishikawa, Xin Wang, Ajay Goel^* (2017). Conference Paper Genome-wide discovery and identification of a novel microrna signature for recurrence prediction in colorectal cancer. Cancer Research.

PMID DOI

Raju Kandimalla^†, Tsuyoshi Ozawa, Feng GAO, Keisuke Hata, Hiroaki Nozawa, Hiroshi Nagata, Daisuke Izumi, Hideo Baba, James W. Fleshman, Xin Wang, Toshiaki Watanabe, Ajay Goel^* (2017). Conference Paper Genome-Wide Analysis Revealed a Robust Gene Expression Signature to Identify Lymph Node Metastasis in Submucosal Colorectal Cancer. Gastroenterology.

Jinsei Miyoshi^†, Shusuke Toden, Jacob Turner, Feng GAO, Raju Kandimalla, Xin Wang, Mitsuro Kanda, Hideo Baba, Yasuhiro Kodera, Ajay Goel^* (2017). Conference Paper A Novel Mirna-Based, Non-Invasive, Diagnostic Panel for Detection of Esophageal Squamous Cell Carcinoma. Gastroenterology.

Tsuyoshi Ozawa^†, Feng GAO, Hiroaki Nozawa, Keisuke Hata, Hiroshi Nagata, Daisuke Izumi, Hideo Baba, Xin Wang, Toshiaki Watanabe, Ajay Goel^* (2017). Conference Paper A Novel Mirna Signature for the Detection of Lymph Node Metastasis in Submucosal Colorectal Cancer Patients. Gastroenterology.

Zhongxu Zhu^†, Guiyuan Han, Hao Huang, Lingli He, Yu Chen, Jia Ke, Feng GAO, Louis Vermeulen, Xin Wang^* (2017). Book Chapter Biomarkers for Precision Medicine. Clinical Chemistry and Laboratory Medicine (CCLM).