Feng GAO

Professor

Sun Yat-sen University

Biography

Dr. Feng Gao is a Professor of Colorectal Surgery at the Sixth Affiliated Hospital of Sun Yat-sen University, a position supported by the university’s prestigious 100 Top Talents Program. After initial training in computer engineering and brief roles in engineering and finance, Dr. Gao earned his Ph.D. in cancer research, specializing in the application of artificial intelligence and big data technologies. He is a core member of the International Cancer Genome Consortium - Accelerated Research in Genomic Oncology (ICGC-ARGO) Colorectal Cancer (CRC) project. His research primarily focuses on creating AI-driven solutions for colorectal cancer diagnosis and prognosis. Dr. Gao also has a strong interest in translating these cutting-edge techniques to other medical disciplines, including diabetes, reproductive health, pediatrics, and dentistry.

Research Interests

Artificial Intelligence
Colorectal Cancer

Education

Joint PhD in Cancer Biology and Bioinformatics
City University of Hong Kong & Cornell University
2015 - 2018
Visiting Student in Computer Science and Electronic Engineering
Kumamoto University
2007 - 2008
BEng in Computer Science and Technology
Shandong University
2005 - 2009

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Yi-Feng Zou^†, Yu-Ming Rong^†, Ying-Xin Tan^†, Jian Xiao, Zhao-Liang Yu, Yu-Feng Chen, Jia Ke, Cheng-Hang LI, Xi Chen, Xiao-Jian Wu, Ping Lan, Xu-Tao Lin, Feng GAO^* (2019). Journal Article A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients. Cancer Cell International.

Hui Chen^†, Feng GAO^†, Mian He^†, Xiao Fan Ding, Aikha M. Wong, Siu Ching Sze, Allen C. Yu, Tingting Sun, Anthony W.-H. Chan, Xin Wang^*, Nathalie Wong^* (2019). Journal Article Long-Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor-Specific Isoforms. Hepatology.

Liuyan Zhang^†, Ping Zhu^†, Yao Tong, Yuzhuo Wang, Haifen Ma, Xuefei Xia, Yu Zhou, Xingguo Zhang^*, Feng GAO^*, Peng Shu^* (2019). Journal Article An immune-related gene pairs signature predicts overall survival in serous ovarian carcinoma. OncoTargets and Therapy.

Feng GAO^†, Wei Wang, Miaomiao Tan, Lina Zhu, Yuchen Zhang, Evelyn Fessler, Louis Vermeulen, Xin Wang^* (2019). Journal Article DeepCC: a novel deep learning-based framework for cancer molecular subtype classification. Oncogenesis.

Bitao Jiang^†, Qingsen Sun^†, Yao Tong, Yuzhuo Wang, Haifen Ma, Xuefei Xia, Yu Zhou, Xingguo Zhang^*, Feng GAO^*, Peng Shu^* (2019). Journal Article An immune-related gene signature predicts prognosis of gastric cancer. Medicine.

Raju Kandimalla^†, Tsuyoshi Ozawa^†, Feng GAO^†, Xin Wang^*, Ajay Goel^*, T1 Colorectal Cancer Study Group (2019). Journal Article Gene expression signature in surgical tissues and endoscopic biopsies identifies high-risk T1 colorectal cancers. Gastroenterology.

Raju Kandimalla^†, Feng GAO^†, Ying Li^†, Hao Huang, Jia Ke, Xin Deng, Linjie Zhao, Shengtao Zhou, Ajay Goel^*, Xin Wang^* (2019). Journal Article RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level. npj Precision Oncology.

Fuminori Sonohara^†, Feng GAO^†, Naoki Iwata, Mitsuro Kanda, Masahiko Koike, Naoki Takahashi, Yasuhide Yamada, Yasuhiro Kodera, Xin Wang^*, Ajay Goel^* (2019). Journal Article Genome-wide discovery of a novel gene-expression signature for the identification of lymph node metastasis in esophageal squamous cell carcinoma. Annals of Surgery.

Wei Wang^†, Raju Kandimalla^†, Hao Huang^†, Lina Zhu, Ying Li, Feng GAO, Ajay Goel, Xin Wang^* (2019). Journal Article Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities. Seminars in Cancer Biology.

Daisuke Izumi^†, Feng GAO^†, Shusuke Toden, Fuminori Sonohara, Mitsuro Kanda, Takatsugu Ishimoto, Yasuhiro Kodera, Xin Wang, Hideo Baba^*, Ajay Goel^* (2019). Journal Article A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer. EBioMedicine.

Rodica P. Bunaciu^†, Robert J. MacDonald, Holly A. Jensen, Feng GAO, Xin Wang, Lynn Johnson, Jeffrey D. Varner, Andrew Yen^* (2018). Journal Article Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML. Leukemia and Lymphoma.

Zhen Xu^†, Peilin Fang, Bingzhe Xu, Yufeng Lu, Jinghui Xiong, Feng GAO, Xin Wang, Jun Fan, Peng Shi^* (2018). Journal Article High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients. Nature Communications.

Kejun Wang^†, Xin DUAN^†, Feng GAO^†, Wei Wang, Liangliang Liu, Xin Wang^* (2018). Journal Article Dissecting cancer heterogeneity based on dimension reduction of transcriptomic profiles using extreme learning machines. PLoS ONE.

Raju Kandimalla^†, Feng GAO^†, Takatoshi Matsuyama, Toshiaki Ishikawa, Hiroyuki Uetake, Naoki Takahashi, Yasuhide Yamada, Carlos Becerra, Scott Kopetz, Xin Wang, Ajay Goel^* (2018). Journal Article Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer. Clinical Cancer Research.

Tsuyoshi Ozawa^†, Raju Kandimalla^†, Feng GAO^†, Hiroaki Nozawa, Keisuke Hata, Hiroshi Nagata, Satoshi Okada, Daisuke Izumi, Hideo Baba, James Fleshman, Xin Wang, Toshiaki Watanabe, Ajay Goel^* (2018). Journal Article A microRNA signature associated with metastasis of T1 colorectal cancers to lymph nodes. Gastroenterology.

Rodica P Bunaciu^†, Robert J MacDonald, Feng GAO, Lynn M Johnson, Jeffrey D Varner, Xin Wang, Sarah Nataraj, Monica L Guzman, Andrew Yen^* (2018). Journal Article Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment. Oncotarget.

Zhongxu Zhu^†, Guiyuan Han, Hao Huang, Lingli He, Yu Chen, Jia Ke, Feng GAO, Louis Vermeulen, Xin Wang^* (2017). Book Chapter Biomarkers for Precision Medicine. Clinical Chemistry and Laboratory Medicine (CCLM).

Xiaobin Zheng^†, Xuanhui Liu, Xiaoli Zhong, Ping Lan, Feng GAO, Jia Ke, Xiao-Jian Wu^* (0001). Su029 INTEGRATING PROGNOSIS-RELATED GENES WITH IMMUNE-RELATED GENE SIGNATURE FOR SURVIVAL STRATIFICATION OF EARLY-STAGE COLORECTAL CANCER.

Min-Yi LV^†, Du CAI, Cheng-Hang LI, Junguo Chen, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan, Feng GAO, Xiaosheng He^* (0001). Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies.

Lan Zhao^†, Feng GAO, Wei Wang, Xin DUAN, Yuchen Zhang, Lina Zhu, Xin Wang^* (0001). Poor-prognosis nasopharyngeal carcinoma as defined by a molecularly distinct subgroup and prediction by a miRNA expression signature.