Feng GAO

Professor

Sun Yat-sen University

Biography

Dr. Feng Gao is a Professor of Colorectal Surgery at the Sixth Affiliated Hospital of Sun Yat-sen University, a position supported by the university’s prestigious 100 Top Talents Program. After initial training in computer engineering and brief roles in engineering and finance, Dr. Gao earned his Ph.D. in cancer research, specializing in the application of artificial intelligence and big data technologies. He is a core member of the International Cancer Genome Consortium - Accelerated Research in Genomic Oncology (ICGC-ARGO) Colorectal Cancer (CRC) project. His research primarily focuses on creating AI-driven solutions for colorectal cancer diagnosis and prognosis. Dr. Gao also has a strong interest in translating these cutting-edge techniques to other medical disciplines, including diabetes, reproductive health, pediatrics, and dentistry.

Research Interests

Artificial Intelligence
Colorectal Cancer

Education

Joint PhD in Cancer Biology and Bioinformatics
City University of Hong Kong & Cornell University
2015 - 2018
Visiting Student in Computer Science and Electronic Engineering
Kumamoto University
2007 - 2008
BEng in Computer Science and Technology
Shandong University
2005 - 2009

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Xin DUAN^†, Wei Wang, Minghui Tang, Feng GAO^*, Xu-Dong Lin^* (2022). Journal Article Dissecting Cellular Heterogeneity Based on Network Denoising of scRNA-seq Using Local Scaling Self-Diffusion. Frontiers in Genetics.

Xu-Tao Lin^†, Qiu-Ning Wu, Si Qin, De-Jun FAN, Min-Yi LV, Xi Chen, Jia-Wei Cai, Jing-Rong Weng, Yi-Feng Zou, Yu-Ming Rong^*, Feng GAO^* (2021). Journal Article Identification of an autophagy-related gene signature for the prediction of prognosis in early-stage colorectal cancer. Frontiers in Genetics.

Yu-Feng Chen^†, Zhao-Liang Yu^†, Min-Yi LV^†, Ze-Rong Cai, Yi-Feng Zou, Ping Lan^*, Xiao-Jian Wu^*, Feng GAO^* (2021). Journal Article Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis. Molecular Medicine.

Raju Kandimalla^†, Wei Wang, Fan Yu, Nianxin Zhou, Feng GAO, Monique Spillman, Lucie Moukova, Ondrej Slaby, Bodour Salhia, Shengtao Zhou^*, Xin Wang^*, Ajay Goel^* (2021). Journal Article OCaMIR—a noninvasive, diagnostic signature for early-stage ovarian cancer: a multi-cohort retrospective and prospective study. Clinical Cancer Research.

Haoyang Li^†, Juexiao Zhou, Yi Zhou, Qiang Chen, Yangyang She, Feng GAO, Ying Xu, Jie-Yu CHEN, Xin Gao^* (2021). Journal Article An interpretable computer-aided diagnosis method for periodontitis from panoramic radiographs. Frontiers in Physiology.

Yu-Feng Chen^†, Zhao-Liang Yu, Min-Yi LV, Bin Zheng, Ying-Xin Tan, Jia Ke, Xuan-Hui Liu, Ze-Rong Cai, Yi-Feng Zou, Ping Lan^*, Xiao-Jian Wu^*, Feng GAO^* (2021). Journal Article Genome-Wide analysis reveals hypoxic microenvironment is associated with immunosuppression in poor survival of stage II/III colorectal cancer patients. Frontiers in Medicine.

Cheng Jin^†, Heng Yu^†, Jia Ke^†, Peirong Ding^†, Yongju Yi, Xiaofeng Jiang, Xin DUAN, Jinghua Tang, Daniel T. Chang, Xiaojian Wu^*, Feng GAO^*, Ruijiang Li^* (2021). Journal Article Predicting treatment response from longitudinal images using multi-task deep learning. Nature Communications.

Xianrui Wu^†, Yunfeng Zhang^†, Tuo Hu, Xiaowen He, Yifeng Zou, Qiling Deng, Jia Ke, Lei Lian, Xiaosheng He, Dezhi Zhao, Xuyu Cai, Zhiwei Chen, Xiaojian Wu, Jian-Bing Fan^*, Feng GAO^*, Ping Lan^* (2021). Journal Article A novel cell-free DNA methylation-based model improves the early detection of colorectal cancer. Molecular Oncology.

Lin Qi^†, Jia Ke, Zhaoliang Yu, Yi Cao, Yuni Lai, Yufeng Chen, Feng GAO^*, Xin Wang^* (2021). Journal Article Identification of prognostic spatial organization features in colorectal cancer microenvironment using deep learning on histopathology images. Medicine in Omics.

Zhao-Liang Yu^†, Yu-Feng Chen^†, Bin Zheng, Ze-Rong Cai, Yi-Feng Zou, Jia Ke, Ping Lan, Feng GAO^*, Xiao-Jian Wu^* (2021). Journal Article Protein-protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer. Cancer Cell International.

Du CAI^†, Xin DUAN^†, Wei Wang, Ze-Ping HUANG, Qi-Qi ZHU, Min-Er ZHONG, Min-Yi LV, Cheng-Hang LI, Wei-Bin KOU, Xiao-Jian Wu^*, Feng GAO^* (2021). Journal Article A metabolism-related radiomics signature for predicting the prognosis of colorectal cancer. Frontiers in Molecular Biosciences.

Zhongxu Zhu^†, Guiyuan Han, Hao Huang, Lingli He, Yu Chen, Jia Ke, Feng GAO, Louis Vermeulen, Xin Wang^* (2020). Book Chapter Genome-wide Discovery of MicroRNA Biomarkers for Cancer Precision Medicine. Detection Methods in Precision Medicine.

Jia Ke^†, Xuan-Hui Liu^†, Xiao-Feng Jiang, Zhen He, Jian Xiao, Bin Zheng, Yu-Feng Chen, Ze-Rong Cai, Xiao-Bin Zheng, Yi-Feng Zou, Ping Lan, Xiao-Jian Wu^*, Feng GAO^* (2020). Journal Article Immune-related gene signature in predicting prognosis of early-stage colorectal cancer patients. European Journal of Surgical Oncology.

Xin DUAN^†, Kejun Wang, Jia Ke, Ping Lan, Feng GAO^*, Xiaojian Wu^* (2020). Journal Article Multiomics-based colorectal cancer molecular subtyping using local scaling network fusion. Journal of Computational Biology.

Xiang Sun^†, Zhijun Ren, Yixian Cun, Cai Zhao, Xianglin Huang, Jiajian Zhou, Rong Hu, Xiaoxi Su, Lu Ji, Peng Li, King Lun Kingston Mak, Feng GAO, Yi Yang, He Xu, Junjun Ding, Nan Cao, Shuo Li, Wensheng Zhang, Ping Lan, Hao Sun, Jinkai Wang, Ping Yuan^* (2020). Journal Article Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers. Nucleic Acids Research.

Asif Rashid^†, Xin DUAN^†, Feng GAO^†, Mengsu Yang^*, Andrew Yen^* (2020). Journal Article Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. Cellular Signalling.

Asif Rashid^†, Xin DUAN^†, Feng GAO^†, Mengsu Yang, Andrew Yen^* (2020). Journal Article Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation. Oncotarget.

Shu-Biao Ye^†, Yi-Kan Cheng^†, Jian-Cong Hu^†, Feng GAO^*, Ping Lan^* (2020). Journal Article Development and validation of an individualized gene expression-based signature to predict overall survival in metastatic colorectal cancer. Annals of Translational Medicine.

Yangyang She^†, Xiangbo Kong, Yaping Ge, Ping Yin, Zhiyong Liu, Jie-Yu CHEN, Feng GAO^*, Silian Fang^* (2020). Journal Article Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma. Cancer Cell International.

Xin DUAN^†, Kejun Wang, Jia Ke, Ping Lan, Feng GAO^*, Xiaojian Wu^* (2019). Journal Article Multiomics-Based Colorectal Cancer Molecular Subtyping Using Local Scaling Network Fusion. Journal of Computational Biology.