Feng GAO

Professor

Sun Yat-sen University

Biography

Dr. Feng Gao is a Professor of Colorectal Surgery at the Sixth Affiliated Hospital of Sun Yat-sen University, a position supported by the university’s prestigious 100 Top Talents Program. After initial training in computer engineering and brief roles in engineering and finance, Dr. Gao earned his Ph.D. in cancer research, specializing in the application of artificial intelligence and big data technologies. He is a core member of the International Cancer Genome Consortium - Accelerated Research in Genomic Oncology (ICGC-ARGO) Colorectal Cancer (CRC) project. His research primarily focuses on creating AI-driven solutions for colorectal cancer diagnosis and prognosis. Dr. Gao also has a strong interest in translating these cutting-edge techniques to other medical disciplines, including diabetes, reproductive health, pediatrics, and dentistry.

Research Interests

Artificial Intelligence
Colorectal Cancer

Education

Joint PhD in Cancer Biology and Bioinformatics
City University of Hong Kong & Cornell University
2015 - 2018
Visiting Student in Computer Science and Electronic Engineering
Kumamoto University
2007 - 2008
BEng in Computer Science and Technology
Shandong University
2005 - 2009

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Wei Lou^†, Xiang Wan, Guanbin Li, Xiaoying Lou, Cheng-Hang LI, Feng GAO, Haofeng Li^* (2024). Journal Article Structure Embedded Nucleus Classification for Histopathology Images. IEEE Transactions on Medical Imaging.

Ngan Pan Bennett Au^†, Tan Wu, Xinyu Chen, Feng GAO, Yuen Tung Yolanda Li, Wing Yip Tam, Kwan Ngok Yu, Daniel H Geschwind, Giovanni Coppola, Xin Wang, Chi Him Eddie Ma^* (2023). Journal Article Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair. Neuron.

Jia Ke^†, Cheng Jin^†, Jinghua Tang^†, Haimei Cao^†, Songbing He^†, Peirong Ding, Xiaofeng Jiang, Hengyu Zhao, Wuteng Cao, Xiaochun Meng, Feng GAO, Ping Lan, Ruijiang Li^*, Xiaojian Wu^* (2023). Journal Article A Longitudinal MRI-Based Artificial Intelligence System to Predict Pathological Complete Response After Neoadjuvant Therapy in Rectal Cancer: A Multicenter Validation Study. Diseases of the Colon & Rectum.

Yanjiao Hua^†, Du CAI, Cole Andrea Shirley, Sien Mo, Ruyun Chen, Feng GAO, Fangying Chen^* (2023). Journal Article A prognostic model for ovarian neoplasms established by an integrated analysis of 1580 transcriptomic profiles. Scientific Reports.

Lin Qi^†, Jie-Ying Liang^†, Zhong-Wu Li, Shao-Yan Xi, Yu-Ni Lai, Feng GAO, Xian-Rui Zhang, De-Shen Wang, Ming-Tao Hu, Yi Cao, Li-Jian Xu, Ronald C K Chan, Bao-Cai Xing, Xin Wang^*, Yu-Hong Li^* (2023). Journal Article Deep learning-derived spatial organization features on histology images predicts prognosis in colorectal liver metastasis patients after hepatectomy. iScience.

Yize Mao^†, Hui Xie^†, Min-Yi LV^†, Qiuxia Yang, Zeyu Shuang, Feng GAO, Shengping Li^*, Lina Zhu^*, Wei Wang^* (2023). Journal Article The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 types of cancer: a system review and novel biomarker investigating. Cancer Immunology, Immunotherapy.

Min-Yi LV^†, Du CAI^†, Cheng-Hang LI^†, Junguo Chen^†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng GAO^* (2023). Journal Article Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies. MedComm.

Yuanyuan Guo^†, Xuantong Zhou, Feng GAO, Minjie Wang, Qi Yang, Xin Li, Zhihua Liu, Aiping Luo^* (2023). Journal Article MiR-423-5p is a novel endogenous control for the quantification of circulating miRNAs in human esophageal squamous cell carcinoma. Heliyon.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiao-Jian Wu^*, Feng GAO^* (2023). Journal Article An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer. Cancer Medicine.

Feng GAO^†, William C Cho, Xin Gao, Wei Wang^* (2023). Journal Article Medical knowledge-assisted machine learning technologies in individualized medicine. Frontiers in Molecular Biosciences.

Fengao Wang^†, Junwei Liu, Feng GAO, Yixue Li^* (2023). Preprint Exploring multi-omics latent embedding spaces for characterizing tumor heterogeneity and tumoral fitness effects. bioRxiv.

Min-Er ZHONG^†, Xin DUAN^†, Ma-Yi-Di-Li Ni-Jia-Ti, Hao-Ning QI, Dong-Wei XU, Du CAI, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Feng GAO^*, Xiaojian Wu^* (2022). Journal Article CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study. Journal of Translational Medicine.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiao-Jian Wu, Feng GAO^* (2022). Journal Article Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature. Frontiers in Genetics.

Feng GAO^†^*, Minhao Hu^†, Min-Er ZHONG^†, Shixiang Feng, Xuwei Tian, Xiaochun Meng, Ze-Ping HUANG, Min-Yi LV, Tao Song, Xiaofan Zhang^*, Xiangguang Zou^*, Xiaojian Wu^* (2022). Journal Article Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images. Medical Image Analysis.

Min-Er ZHONG^†, Ze-Ping HUANG^†, Xun WANG^†, Du CAI, Cheng-Hang LI, Feng GAO^*, Xiao-Jian Wu^*, Wei Wang^* (2022). Journal Article A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer. Frontiers in Oncology.

Cheng-Hang LI^†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO^* (2022). Journal Article Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer. Frontiers in Genetics.

Qian Cai^†, Yi-Ze Mao^†, Si-Qi Dai^†, Feng GAO^†, Qian Xiao, Wan-Ming Hu, Tao Qin, Qiu-Xia Yang, Zhao-Zhou Li, Du CAI, Min-Er ZHONG, Ke-Feng Ding^*, Xiaojian Wu^*, Rong Zhang^* (2022). Journal Article The growth pattern of liver metastases on MRI predicts early recurrence in patients with colorectal cancer: a multicenter study. European Radiology.

Min-Yi LV^†, Wei Wang^†, Min-Er ZHONG^†, Du CAI, De-Jun FAN, Cheng-Hang LI, Wei-Bin KOU, Ze-Ping HUANG, Xin DUAN, Chu-Ling HU, Qi-Qi ZHU, Xiao-Sheng He, Feng GAO^* (2022). Journal Article DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients. Frontiers in Genetics.

Jinsei Miyoshi^†, Zhongxu Zhu^†, Aiping Luo^†, Shusuke Toden^†, Xuantong Zhou, Daisuke Izumi, Mitsuro Kanda, Tetsuji Takayama, Iqbal M. Parker, Minjie Wang, Feng GAO, Ali H. Zaidi, Hideo Baba, Yasuhiro Kodera, Yongping Cui, Xin Wang^*, Zhihua Liu^*, Ajay Goel^* (2022). Journal Article A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study. Molecular Cancer.

Tongtong Kan^†, Shupeng Zhang, Shengtao Zhou, Ya Zhang, Yun Zhao, Yinghua Gao, Tao Zhang, Feng GAO, Xin Wang, Linjie Zhao, Mengsu Yang^* (2022). Journal Article Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence. Oncogene.