Feng GAO

Professor

Sun Yat-sen University

Biography

Dr. Feng Gao is a Professor of Colorectal Surgery at the Sixth Affiliated Hospital of Sun Yat-sen University, a position supported by the university’s prestigious 100 Top Talents Program. After initial training in computer engineering and brief roles in engineering and finance, Dr. Gao earned his Ph.D. in cancer research, specializing in the application of artificial intelligence and big data technologies. He is a core member of the International Cancer Genome Consortium - Accelerated Research in Genomic Oncology (ICGC-ARGO) Colorectal Cancer (CRC) project. His research primarily focuses on creating AI-driven solutions for colorectal cancer diagnosis and prognosis. Dr. Gao also has a strong interest in translating these cutting-edge techniques to other medical disciplines, including diabetes, reproductive health, pediatrics, and dentistry.

Research Interests

Artificial Intelligence
Colorectal Cancer

Education

Joint PhD in Cancer Biology and Bioinformatics
City University of Hong Kong & Cornell University
2015 - 2018
Visiting Student in Computer Science and Electronic Engineering
Kumamoto University
2007 - 2008
BEng in Computer Science and Technology
Shandong University
2005 - 2009

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Ke-Cheng WU^†, Zhaohu Xing, Zerong Cai, Feng GAO, Wenxue Li, Lei Zhu^* (2025). Conference Paper FSA-Net: Fractal-driven Synergistic Anatomy-aware Network for Segmenting White Line of Toldt in Laparoscopic Images. MICCAI.

Jing Yang^†, Yuxi Ma, Jin-Gang Yu, Feng GAO, Shu-Ting YANG, Du CAI, Jiacheng Wang^*, Liansheng Wang^* (2025). Conference Paper Bridging Knowledge Discrepancy in Retinal Image Analysis through Federated Multi-Task Learning. MICCAI.

Riyu Qiu^†, Kun Xia, Feng GAO, Shu-Ting YANG, Du CAI, Jiacheng Wang, Yinran Chen^*, Liansheng Wang^* (2025). Conference Paper Accurate Boundary Alignment and Realism Enhancement for Colonoscopic Polyp Image-Mask Pair Generation. MICCAI.

Zhengran Zhou^†, Richard Mortensen^†, Peishan Hu^†, Bo Jin, Xiao-Bin Zheng, Xiao Li, James Schilling, C. James Chou, Karl G. Sylvester, Yanghai Cong, Xiaojian Wu, Feng GAO^*, Xuefeng B. Ling^*, Xuanhui Liu^* (2025). Journal Article A plasma metabolite-based test to detect minimal residual disease in post-surgery patients with colorectal cancer. iScience.

Ren-De HUANG^†, Jiang Li^†, Qi Cao^†, Lixia Wang^†, Zhixiong Shao, Haochun Yang, Xinlei Zhang, Chuanlai Yang, Xiangya Kong, Qiuyue Gu, Jianmin Wu, Tsan- Yu Chiu, Penghu Lian^*, Kui Wu^*, Feng GAO^*, Zhongxu Zhu^* (2025). Journal Article PCsRNAdb: a comprehensive resource of small noncoding RNAs across cancers. NAR.

DOI Code Project

Yibin Zhao^†, Hao Liu^†, Yu Wang, Jie Shen, Yang Le, Peiyuan Li, Yuxiang Zhao^*, Feng GAO^*, Wei Cui^* (2025). Journal Article Immunological Microenvironment Differences Between Left and Right Colon Cancer: Dynamic Interactions of CASC15+KLK6+ Epithelial Subpopulation with T Cells and Mast Cells. IJS.

Chong-Xiang GAO^†, Du CAI, Jianguang Qiu^*, Feng GAO^* (2025). Journal Article The role of tertiary lymphoid structures in renal cell carcinoma: From predictive biomarker to therapeutic target. Clin Transl Disc.

Jing Yang^†, Du CAI^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning. Advanced Science.

Du CAI^†, Hao-Ning QI^†, Qiuxia Yang^†, Huayu Li^†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article Personalized risk stratification in colorectal cancer via PIANOS system. Nature Communications.

Jia Ke^†, Ying Li^†, Lin Qi^†, Xiang Li, Wei Wang, Sanne Ten Hoorn, Yin Zhu, Hao Huang, Feng GAO, Louis Vermeulen, Xin Wang^* (2025). Journal Article Poor-prognosis young-onset colorectal cancer is defined by the mesenchymal subtype and can be predicted by integrating molecular and histopathological characteristics. ESMO Gastrointest Oncol.

Feng GAO^†, Junxiang Ding^†, Bao-Wen GAI^†, Du CAI^†, Chu-Ling HU, Feng-Ao Wang, Ruikun He, Junwei Liu^*, Yixue Li^*, Xiao-Jian Wu^* (2025). Journal Article Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer. Advanced Science.

Xuefeng Zhang^†, Bin Yan, Zhaohu Xing, Feng GAO, Yuandong Tao, Zhenyan Han, Weiming Wang^*, Lei Zhu^* (2025). Journal Article HADiff: hierarchy aggregated diffusion model for pathology image segmentation. TVC.

Junwei Liu^†, Xiaoping Cen^†, Chenxin Yi, Feng-Ao Wang, Junxiang Ding, Jinyu Cheng, Qinhua Wu, Bao-Wen GAI, Yiwen Zhou, Ruikun He, Feng GAO^*, Yixue Li^* (2025). Journal Article Challenges in AI-driven Biomedical Multimodal Data Fusion and Analysis. Genomics Proteomics Bioinformatics.

Jinsei Miyoshi^†, Alessandro Mannucci^†, Marco Scarpa, Feng GAO, Shusuke Toden, Timothy Whitsett, Landon J Inge, Ross M Bremner, Tetsuji Takayama, Yulan Cheng, Teodoro Bottiglieri, Iris D Nagetaal, Martha J Shrubsole, Ali H Zaidi, Xin Wang, Helen G Coleman, Lesley a Anderson, Stephen J Meltzer, Ajay Goel^* (2025). Journal Article Liquid biopsy to identify Barrett's oesophagus, dysplasia and oesophageal adenocarcinoma: the EMERALD multicentre study. Gut.

PMID Trial Registration DOI Dataset

Zhaohu Xing^†, Tian Ye, Yijun Yang, Du CAI, Bao-Wen GAI, Xiao-Jian Wu^*, Feng GAO^*, Lei Zhu^* (2025). Journal Article SegMamba-V2: Long-range Sequential Modeling Mamba For General 3D Medical Image Segmentation. TMI.

Xinzhe Zhao^†, Hongda Zhang, Hengyu Zhao, Decan Kong, Weijie Zeng, Feng GAO, Xiaochun Meng, Jia Ke^* (2024). Journal Article Anatomic association between the gastrocolic trunk of Henle and right colic artery by high-quality CT venography. Scientific Reports.

Zhen Xie^†, Du CAI^†, Runyi Ye, Zhen Shan, Ying Lin, Feng GAO^*, Nan Shao^*, Xiaying Kuang^* (2024). Journal Article Integrated immune-related gene signature predicts clinical outcome for patients with Luminal B breast cancer. Gland Surgery.

Feng Guo^†, Xianglin Ji^†, Chuxiao Xiong, Hailiang Sun, Zhenghua Liang, Richard Yan-Do, Bao-Wen GAI, Feng GAO, Linfeng Huang, Zhongping Li, Becki Yi Kuang, Peng Shi^* (2024). Journal Article Single-cell encoded gene silencing for high-throughput combinatorial siRNA screening. Nature Communications.

Jia-Xin LEI^†, Run-Xian WANG^†, Chu-Ling HU, Xiaoying Lou, Min-Yi LV, Cheng-Hang LI, Bao-Wen GAI, Xiao-Jian Wu^*, Ruoxu Dou^*, Du CAI^*, Feng GAO^* (2024). Journal Article Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study. International Journal of Surgery.

Feng-Ao Wang^†, Zhenfeng Zhuang^†, Feng GAO^†, Ruikun He, Shaoting Zhang, Liansheng Wang^*, Junwei Liu^*, Yixue Li^* (2024). Journal Article TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology. Genome Biology.