Chu-Ling HU

PhD Student

Sun Yat-sen University

Biography

I am a PhD student focusing on AI-driven colorectal cancer research and clinically useful model development.

Research Interests

Colorectal Cancer
Artificial Intelligence

Education

Doctor of Medicine in Surgery
Sun Yat-sen University
2021 - now
Bachelor of Medicine in Clinical Medicine
Sun Yat-sen University
2016 - 2021

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Chu-Ling HU^†, Du CAI^†, Weiqiang You^†, Zhengran Zhou^†, Junwei Liu, Cheng-Hang LI, Min-Yi LV, Bao-Wen GAI, Chong Chen, Xinxin Huang, Run-Xian WANG, Xiao-Jian Wu^*, Peishan Hu^*, Feng GAO^* (2026). Journal Article Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition. Cancer Letters.

Source Document DOI

Chong Chen^†, Du CAI^†, Xuanhui Liu^†, Yifan Zheng, Xinxin Huang, Dongwen Chen, Jiawei Cai, Yiran Bie, Zhengran Zhou, Chu-Ling HU, Zhengyu Wei, Kuntai Cai, Ting Li, Shuzhen Luo, Dongbing Liu, Kui Wu, Zerong Cai, Feng GAO, Xiaojian Wu^*, Peishan Hu^* (2026). Journal Article Lactylation of SLC26A3 in the acidic tumor microenvironment promotes malignant progression of colorectal carcinoma. Cell Death & Disease.

Bao-Wen GAI^†, Xin DUAN, Cheng-Hang LI, Chu-Ling HU, Min-Yi LV, Jia-Xin LEI, Run-Xian WANG, Feng GAO^*, Du CAI^* (2026). Journal Article Translating Molecular Subtypes into Cost-Effective Radiogenomic Biomarkers for Prognosis of Colorectal Cancer. Diagnostics.

Jing Yang^†, Du CAI^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning. Advanced Science.

Du CAI^†, Hao-Ning QI^†, Qiuxia Yang^†, Huayu Li^†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article Personalized risk stratification in colorectal cancer via PIANOS system. Nature Communications.

Feng GAO^†, Junxiang Ding^†, Bao-Wen GAI^†, Du CAI^†, Chu-Ling HU, Feng-Ao Wang, Ruikun He, Junwei Liu^*, Yixue Li^*, Xiao-Jian Wu^* (2025). Journal Article Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan-Cancer. Advanced Science.

Jia-Xin LEI^†, Run-Xian WANG^†, Chu-Ling HU, Xiaoying Lou, Min-Yi LV, Cheng-Hang LI, Bao-Wen GAI, Xiao-Jian Wu^*, Ruoxu Dou^*, Du CAI^*, Feng GAO^* (2024). Journal Article Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study. International Journal of Surgery.

Min-Yi LV^†, Du CAI^†, Cheng-Hang LI^†, Junguo Chen^†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng GAO^* (2023). Journal Article Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies. MedComm.

Min-Yi LV^†, Du CAI, Cheng-Hang LI, Junguo Chen, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan, Feng GAO, Xiaosheng He^* (2023). Conference Paper Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies. Gastroenterology.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiao-Jian Wu^*, Feng GAO^* (2023). Journal Article An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer. Cancer Medicine.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiao-Jian Wu, Feng GAO^* (2022). Journal Article Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature. Frontiers in Genetics.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiaojian Wu, Feng GAO^* (2022). Conference Paper A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.. Journal of Clinical Oncology.

Cheng-Hang LI^†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO^* (2022). Journal Article Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer. Frontiers in Genetics.

Min-Yi LV^†, Wei Wang^†, Min-Er ZHONG^†, Du CAI, De-Jun FAN, Cheng-Hang LI, Wei-Bin KOU, Ze-Ping HUANG, Xin DUAN, Chu-Ling HU, Qi-Qi ZHU, Xiao-Sheng He, Feng GAO^* (2022). Journal Article DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients. Frontiers in Genetics.

Qi-Qi ZHU^†, Du CAI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^* (2021). Conference Paper Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.. Journal of Clinical Oncology.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^* (2021). Conference Paper Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.. Journal of Clinical Oncology.

Min-Er ZHONG^†, Du CAI, De-Jun FAN, Wei Wang, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xiaojian Wu, Feng GAO^* (2021). Conference Paper A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer. Journal of Clinical Oncology.