Cheng-Hang LI

Research Assistant

Cancer Institution PKU & HKUST Medical Center

Biography

I am a research assistant focusing on deep learning, multimodal feature fusion, and medical AI system development.

Research Interests

Deep Learning
Feature Fusion

Education

Mphil in Artificial Intelligence
The Hong Kong University of Science and Technology Guangzhou
2022 - 2024
MEng in Computer Science and Technology
Sun Yat-sen University
2019 - 2022
BEng in Polymer Materials and Science
Sichuan University
2015 - 2019

Lab highlights

Highlighted publications

2026 Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

2025 Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

2025 Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

All related publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Journal Article 2026 Cancer Letters

Multi-omics driven immune classification of colorectal cancer: Implications for immunotherapy efficacy prediction and enhancement with WNT signaling inhibition

Chu-Ling HU^†, Du CAI^†, Weiqiang You^†, Zhengran Zhou^†, Junwei Liu, Cheng-Hang LI, Min-Yi LV, Bao-Wen GAI, Chong Chen, Xinxin Huang, Run-Xian WANG, Xiao-Jian Wu^*, Peishan Hu^*, Feng GAO^*

Source Document DOI

Journal Article 2026 Diagnostics

Translating Molecular Subtypes into Cost-Effective Radiogenomic Biomarkers for Prognosis of Colorectal Cancer

Bao-Wen GAI^†, Xin DUAN, Cheng-Hang LI, Chu-Ling HU, Min-Yi LV, Jia-Xin LEI, Run-Xian WANG, Feng GAO^*, Du CAI^*

Journal Article 2025 Cancer Science

Decoding Senescence-Driven Heterogeneity in Early-Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Du CAI^†, Ming-Ru MAI^†, Ren-De HUANG^†, Hao-Ning QI, Xingzhi Feng, Qianling Gao, Yin-Meng ZHANG, Cheng-Hang LI, Xiaojian Wu^*, Yize Mao^*, Zihuan Yang^*, Feng GAO^*

Journal Article 2025 Advanced Science

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning

Jing Yang^†, Du CAI^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng GAO^*, Xiaojian Wu^*

Journal Article 2025 Nature Communications

Personalized risk stratification in colorectal cancer via PIANOS system

Du CAI^†, Hao-Ning QI^†, Qiuxia Yang^†, Huayu Li^†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao^*, Feng GAO^*, Xiaojian Wu^*

Journal Article 2024 International Journal of Surgery

Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study

Jia-Xin LEI^†, Run-Xian WANG^†, Chu-Ling HU, Xiaoying Lou, Min-Yi LV, Cheng-Hang LI, Bao-Wen GAI, Xiao-Jian Wu^*, Ruoxu Dou^*, Du CAI^*, Feng GAO^*

Journal Article 2024 IEEE Transactions on Medical Imaging

Structure Embedded Nucleus Classification for Histopathology Images

Wei Lou^†, Xiang Wan, Guanbin Li, Xiaoying Lou, Cheng-Hang LI, Feng GAO, Haofeng Li^*

Journal Article 2023 MedComm

Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies

Min-Yi LV^†, Du CAI^†, Cheng-Hang LI^†, Junguo Chen^†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng GAO^*

Conference Paper 2023 Gastroenterology

Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies

Min-Yi LV^†, Du CAI, Cheng-Hang LI, Junguo Chen, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan, Feng GAO, Xiaosheng He^*

Journal Article 2023 Cancer Medicine

An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiao-Jian Wu^*, Feng GAO^*

Journal Article 2022 Journal of Translational Medicine

CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study

Min-Er ZHONG^†, Xin DUAN^†, Ma-Yi-Di-Li Ni-Jia-Ti, Hao-Ning QI, Dong-Wei XU, Du CAI, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Feng GAO^*, Xiaojian Wu^*

Journal Article 2022 Frontiers in Genetics

Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiao-Jian Wu, Feng GAO^*

Journal Article 2022 Frontiers in Oncology

A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer

Min-Er ZHONG^†, Ze-Ping HUANG^†, Xun WANG^†, Du CAI, Cheng-Hang LI, Feng GAO^*, Xiao-Jian Wu^*, Wei Wang^*

Conference Paper 2022 Journal of Clinical Oncology

A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiaojian Wu, Feng GAO^*

Journal Article 2022 Frontiers in Genetics

Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer

Cheng-Hang LI^†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO^*

Conference Paper 2022 Gastroenterology

PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer

Du CAI^†, Hao-Ning QI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Xiaojian Wu, Feng GAO^*

Journal Article 2022 Frontiers in Genetics

DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients

Min-Yi LV^†, Wei Wang^†, Min-Er ZHONG^†, Du CAI, De-Jun FAN, Cheng-Hang LI, Wei-Bin KOU, Ze-Ping HUANG, Xin DUAN, Chu-Ling HU, Qi-Qi ZHU, Xiao-Sheng He, Feng GAO^*

Conference Paper 2021 Journal of Clinical Oncology

Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer.

Qi-Qi ZHU^†, Du CAI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^*

Conference Paper 2021 Journal of Clinical Oncology

Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^*

Conference Paper 2021 Journal of Clinical Oncology

A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer

Min-Er ZHONG^†, Du CAI, De-Jun FAN, Wei Wang, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xiaojian Wu, Feng GAO^*