Cheng-Hang LI

Research Assistant

Cancer Institution PKU & HKUST Medical Center

Biography

Chenghang LI is a master of Computer Science and Technology co-supervised by the Sixth Affiliated Hospital and School Computer Science and Engineering at Sun Yat-sen University. He is interested in applying advanced machine learning technologies to medical research. His current research topics include supervised learning of cancer molecular subtypes with multi-omics data, survival analysis with genomic data and computational pathology images based on deep learning. He completed an MPhil in Artificial Intelligence at the Hong Kong University of Science and Technology (Guangzhou), where he deepened his expertise in deep learning and its applications in pathology and radiology. Now, he works at the Cancer Institute of Peking University & HKUST Medical Center. In his current role, he continues to focus on integrating artificial intelligence and machine learning techniques into oncology research.

Research Interests

Deep Learning
Feature Fusion

Education

Mphil in Artificial Intelligence
The Hong Kong University of Science and Technology Guangzhou
2022 - 2024
MEng in Computer Science and Technology
Sun Yat-sen University
2019 - 2022
BEng in Polymer Materials and Science
Sichuan University
2015 - 2019

Related Publications

† First or co-first author, * Corresponding or co-corresponding author, bold names are lab members

Jing Yang^†, Du CAI^†, Junwei Liu^†, Zhenfeng Zhuang^†, Yibin Zhao, Feng-Ao Wang, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Yiping Chen, Yixue Li, Liansheng Wang^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self-Supervised Learning. Advanced Science.

Du CAI^†, Hao-Ning QI^†, Qiuxia Yang^†, Huayu Li^†, Cheng-Hang LI, Chu-Ling HU, Bao-Wen GAI, Xu Zhang, Yize Mao^*, Feng GAO^*, Xiaojian Wu^* (2025). Journal Article Personalized risk stratification in colorectal cancer via PIANOS system. Nature Communications.

Jia-Xin LEI^†, Run-Xian WANG^†, Chu-Ling HU, Xiaoying Lou, Min-Yi LV, Cheng-Hang LI, Bao-Wen GAI, Xiao-Jian Wu^*, Ruoxu Dou^*, Du CAI^*, Feng GAO^* (2024). Journal Article Deciphering Tertiary Lymphoid Structure Heterogeneity Reveals Prognostic Signature and Therapeutic Potentials for Colorectal Cancer: A Multicenter Retrospective Cohort Study. International Journal of Surgery.

Wei Lou^†, Xiang Wan, Guanbin Li, Xiaoying Lou, Cheng-Hang LI, Feng GAO, Haofeng Li^* (2024). Journal Article Structure Embedded Nucleus Classification for Histopathology Images. IEEE Transactions on Medical Imaging.

Min-Yi LV^†, Du CAI^†, Cheng-Hang LI^†, Junguo Chen^†, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan^*, Xiaojian Wu^*, Xiaosheng He^*, Feng GAO^* (2023). Journal Article Senescence-based colorectal cancer subtyping reveals distinct molecular characteristics and therapeutic strategies. MedComm.

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiao-Jian Wu^*, Feng GAO^* (2023). Journal Article An immune, stroma, and epithelial--mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II--III colorectal cancer. Cancer Medicine.

Min-Er ZHONG^†, Xin DUAN^†, Ma-Yi-Di-Li Ni-Jia-Ti, Hao-Ning QI, Dong-Wei XU, Du CAI, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Feng GAO^*, Xiaojian Wu^* (2022). Journal Article CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study. Journal of Translational Medicine.

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiao-Jian Wu, Feng GAO^* (2022). Journal Article Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature. Frontiers in Genetics.

Min-Er ZHONG^†, Ze-Ping HUANG^†, Xun WANG^†, Du CAI, Cheng-Hang LI, Feng GAO^*, Xiao-Jian Wu^*, Wei Wang^* (2022). Journal Article A transcription factor signature can identify the CMS4 subtype and stratify the prognostic risk of colorectal cancer. Frontiers in Oncology.

Cheng-Hang LI^†, Du CAI, Min-Er ZHONG, Min-Yi LV, Ze-Ping HUANG, Qi-Qi ZHU, Chu-Ling HU, Hao-Ning QI, Xiaojian Wu, Feng GAO^* (2022). Journal Article Multi-size deep learning based preoperative computed tomography signature for prognosis prediction of colorectal cancer. Frontiers in Genetics.

Min-Yi LV^†, Wei Wang^†, Min-Er ZHONG^†, Du CAI, De-Jun FAN, Cheng-Hang LI, Wei-Bin KOU, Ze-Ping HUANG, Xin DUAN, Chu-Ling HU, Qi-Qi ZHU, Xiao-Sheng He, Feng GAO^* (2022). Journal Article DNA Repair–Related Gene Signature in Predicting Prognosis of Colorectal Cancer Patients. Frontiers in Genetics.

Du CAI^†, Xin DUAN^†, Wei Wang, Ze-Ping HUANG, Qi-Qi ZHU, Min-Er ZHONG, Min-Yi LV, Cheng-Hang LI, Wei-Bin KOU, Xiao-Jian Wu^*, Feng GAO^* (2021). Journal Article A metabolism-related radiomics signature for predicting the prognosis of colorectal cancer. Frontiers in Molecular Biosciences.

Yi-Feng Zou^†, Yu-Ming Rong^†, Ying-Xin Tan^†, Jian Xiao, Zhao-Liang Yu, Yu-Feng Chen, Jia Ke, Cheng-Hang LI, Xi Chen, Xiao-Jian Wu, Ping Lan, Xu-Tao Lin, Feng GAO^* (2019). Journal Article A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients. Cancer Cell International.

Min-Yi LV^†, Du CAI, Cheng-Hang LI, Junguo Chen, Guanman Li, Chu-Ling HU, Bao-Wen GAI, Jia-Xin LEI, Ping Lan, Feng GAO, Xiaosheng He^* (0001). Senescence-Based Colorectal Cancer Subtyping Reveals Distinct Molecular Characteristics and Therapeutic Strategies.

Du CAI^†, Hao-Ning QI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Xiaojian Wu, Feng GAO^* (0001). PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer.

Xin DUAN^†, Du CAI, Yufeng Chen, Qi-Qi ZHU, Ze-Ping HUANG, Cheng-Hang LI, Xiaojian Wu, Feng GAO^* (0001). Integrating diffusion components of multi-omics datasets with application to cancer molecular subtyping.

Qi-Qi ZHU^†, Du CAI, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^* (0001). Identifying an immune-related gene-pair for prognosis prediction of metastatic colorectal cancer..

Du CAI^†, Wei Wang, Min-Er ZHONG, De-Jun FAN, Xuanhui Liu, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xin DUAN, Xiaojian Wu, Feng GAO^* (0001). Deep learning to identify a gene signature associated with molecular subtypes that predicts prognosis in colorectal cancer..

Chu-Ling HU^†, Du CAI, Min-Er ZHONG, De-Jun FAN, Cheng-Hang LI, Min-Yi LV, Ze-Ping HUANG, Wei Wang, Xiaojian Wu, Feng GAO^* (0001). A tumor immune microenvironment-related lncRNA signature for the prognosis and immunotherapeutic sensitivity prediction in colorectal cancer..

Min-Er ZHONG^†, Du CAI, De-Jun FAN, Wei Wang, Cheng-Hang LI, Ze-Ping HUANG, Qi-Qi ZHU, Min-Yi LV, Chu-Ling HU, Xiaojian Wu, Feng GAO^* (0001). A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left-and right-sided colon cancer.